Thalidomide-5-COOH|CAS 1216805-11-6|DC Chemicals

Cas No.:	1216805-11-6
Chemical Name:	Thalidomide-5-COOH
SMILES:	O=C1CCC(N2C(=O)C3=CC=C(C(=O)O)C=C3C2=O)C(=O)N1
Formula:	C₁₄H₁₀N₂O₆
M.Wt:	302.24
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC47889	Thalidomide-5-NH2-CH2-COOH	Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for the treatment of one or more diseases (extracted from patent WO2021170109A1) .
DC47206	Thalidomide-5-CH2-NH2 hydrochloride	Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
DC46956	Thalidomide-5-COOH	Thalidomide-5-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-COOH can be connected to the ligand for protein by a linker to form PROTACs.
DC45698	Lenalidomide-4-aminomethyl hydrochloride	Lenalidomide-4-aminomethyl hydrochloride is the Lenalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Lenalidomide-4-aminomethyl hydrochloride can be connected to the ligand for protein by a linker to form PROTAC
DC11579	VH032	VH-032 (VHL ligand 1) is a VHL ligand for PROTAC and potent, small molecule inhibitor of the VHL/HIF-1α interaction with Kd of 185 nM..
DC11578	VHL Ligand 3	A VHL ligand for PROTAC..