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FAPI-34

  Cat. No.:  DC46245   Featured
Chemical Structure
2374782-07-5
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More than 5000 active chemicals with high quality for research!
Field of application
FAPI-34 is a fibroblast-activating protein (FAP) inhibitor with favorable pharmacokinetic and biochemical properties. (patent WO2019154886A1).
Cas No.: 2374782-07-5
Chemical Name: FAPI-34
Synonyms: FAPI-34;HY-139401;2374782-07-5;MS-32026;DA-63371;CS-0200386;SCHEMBL22966423;G18309;EX-A5969;(3S)-3-[[2-[2-[[[2-[4-[3-[4-[[2-[(2S)-2-cyano-4,4-difluoropyrrolidin-1-yl]-2-oxoethyl]carbamoyl]quinolin-6-yl]oxypropyl]piperazin-1-yl]-2-oxoethyl]-[[1-[2-oxo-2-[[(1S)-1,3,3-tricarboxypropyl]amino]ethyl]imidazol-2-yl]methyl]amino]methyl]imidazol-1-yl]acetyl]amino]propane-1,1,3-tricarboxylic acid;AKOS040754875
SMILES: N1(CC(=O)N[C@H](C(O)=O)CC(C(=O)O)C(=O)O)C(CN(CC(=O)N2CCN(CCCOC3=CC=C4C(=C3)C(C(=O)NCC(=O)N3CC(F)(C[C@H]3C#N)F)=CC=N4)CC2)CC2N(CC(=O)N[C@H](C(O)=O)CC(C(=O)O)C(=O)O)C=CN=2)=NC=C1
Formula: C50H57F2N13O18
M.Wt: 1166.06
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC46245 FAPI-34 FAPI-34 is a fibroblast-activating protein (FAP) inhibitor with favorable pharmacokinetic and biochemical properties. (patent WO2019154886A1).
DC40358 MK-6240 Precursor MK-6240 Precursor (6e) serves as a key intermediate in the synthesis of ​**[18F]-MK-6240**, a highly selective ​tau-targeting PET imaging agent. The radiolabeled compound, ​**[18F]-MK-6240**, is specifically designed for detecting ​neurofibrillary tangles (NFTs)—a hallmark pathology of ​Alzheimer’s disease and other tauopathies.
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