Gly-Cyclopropane-Exatecan|CAS 2414254-49-0|DC Chemicals

Cas No.:	2414254-49-0
Chemical Name:	Gly-Cyclopropane-Exatecan
SMILES:	NCC(NCOC(C1CC1)C(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O
Formula:	C₃₂H₃₄FN₅O₇
M.Wt:	619.64
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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DC72753	Gly-Cyclopropane-Exatecan	Gly-Cyclopropane-Exatecan involves in the synthesis of anti-B7-H4 ADC, containing Exatecan, a DNA Topoisomerase I inhibitor. Gly-Cyclopropane-Exatecan participated in the formation of the ADC hu2F7-Exatecan (compound 34), which showed antitumor activity in vivo and in vitro.
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