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Cat. No. Product Name Field of Application Chemical Structure
DC67592 Pitstop 2-100 Featured
DC67591 4-(2-(5-(3,5-dimethylisoxazol-4-yl)-2-(3-fluoro-4-(prop-2-yn-1-yloxy)phenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine Featured
DC67589 Desethylatrazine-d7 Featured
Desethylatrazine-d7 is the deuterium labeled Desethylatrazine.
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DC67588 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-(4-methoxyphenyl)-N-[(1R)-1-phenylethyl]- Featured
DC67587 3-chloro-N-[[(3-chloro-5-fluorophenyl)amino]thioxomethyl]benzamide Featured
DC73393 alpha-NETA Featured
alpha-NETA (α-NETA) is a small molecule antagonist of chemerin receptor chemokine-like receptor 1 (CMKLR1), inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 with IC50 of 4.9 uM.
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DC60631 T-10418 Featured
T-10418 is a potent and selective G2A agonist with EC50 of 0.82 μM. T-10418 exhibits higher potency than the reference and natural ligand 9-HODE and high selectivity among G protein-coupled receptors. T-10418 is a suitable candidate for in vivo studies on therapeutic potential of G2A agonism.
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DC26092 PF-04455242 hydrochloride Featured
PF-04455242 is a potent, selective κ-opioid receptor (KOR) antagonist with Ki of 3 nM/21 nM/22 nM for hKOR/rKOR/mKOR, respectively.
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DC23423 PF-04455242 Featured
PF-04455242 is a potent, selective κ-opioid receptor (KOR) antagonist with Ki of 3 nM/21 nM/22 nM for hKOR/rKOR/mKOR, respectively.
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DC40974 GSK717 Featured
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.
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DC11594 HDAC8-IN-20a Featured
HDAC8-IN-20a is a potent, selective HDAC8 inhibitor with IC50 of 27 nM.
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DC43231 Phenamil Featured
Irreversible inhibitor of amiloride-sensitive Na channels; derivative of amiloride
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DC34406 T62 Featured
T62 is an allosteric enhancer of A1 adenosine receptor.
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DC21398 AI-2 Featured
Nrf2 acticatior AI-2 is a small-molecule inducer of the antioxidant response element (ARE) that activates and stabilizes Nrf2 by covalently modifying Keap1.
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DC47307 Defibrotide sodium Featured
Defibrotide sodium is a complex mixture of single stranded polydeoxyribonucleotides. Defibrotide sodium has liver protection, anti-inflammatory, antithrombotic, profibrinolytic, and anti-ischemic properties. Defibrotide sodium can be used for sinusoidal obstruction syndrome (SOS)/veno-occlusive disease (VOD) research.
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DC26208 Remdesivir metabolite(GS-441524) Featured
Remdesivir metabolite.Remdesivir blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 Nm,and also showed potent activity blocking 2019-nCov(Coronavirus).
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DC73788 K161 Featured
K161 is a potent, pan-SHIP1/2 inhibitor with IC50 of 1.5- 6 uM and 6.5-13 uM, respectively.
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DC60852 PVTX-405 Featured
PVTX-405 is a potent, effective, highly selective, and orally efficacious IKZF2 molecular glue degrader with DC50 of  0.7 nM. PVTX-405 in combination with anti-PD1 or anti-LAG3 significantly increases animal survival compared to anti-PD1 or anti-LAG3 alone.
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DC73944 CK147 Featured
CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro.
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DC39823 Diphenylterazine (DTZ) Featured
Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios.
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DC10610 CycLuc1(Luciferase substrate) Featured
CycLuc1 is a luciferase substrate which offers brighter bioluminescence and improved imaging in mouse models at lower doses than the standard D-luciferin.
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DC65436 AkaLumine hydrochloride Featured
AkaLumine hydrochloride is a luciferin analogue, with a Km of 2.06 μM for recombinant Fluc protein.
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DC34025 AkaLumine Featured
AkaLumine is a luciferin analogue. The bioluminescence produced by AkaLumine in reactions with native firefly luciferase is in the near-infrared wavelength ranges (λmax=677?nm), and yields significantly increased target-detection sensitivity from deep tissues with maximal signals attained at very low concentrations, as compared with D-luciferin and emerging synthetic luciferin CycLuc1.
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DC85555 2-Octyldecyl 6-[[4-(decyloxy)-4-oxobutyl](2- hydroxyethyl)amino]hexanoate Featured
YK-009 is a novel ionizable lipid for mRNA delivery. Comparisons of YK009-LNP-mRNA and commercial MC3-LNP-mRNA showed that YK009-LNP-mRNA vaccines had good biodistribution patterns, favorable tissue clearance, and high delivery efficiency. Furthermore, our study proved that YK009-LNP-Omicron mRNA could trigger a robust immune response and immune protection against the SARS-CoV-2 Omicron variant.
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DC11457 Tos-Gly-Pro-Arg-pNA(Thrombin substrate) Featured
Tos-Gly-Pro-Arg-pNa is a chromogenic substrate for Thrombin.
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DC45080 Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride (factor Xa specific chromogenic substrate) Featured
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate.
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DC67319 S-2403(chromogenic substrate for plasmin and streptokinase-activated plasminoge) Featured
S-2403 is a chromogenic substrate for plasmin and streptokinase-activated plasminoge
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DC67320 S-2732 Suc-lle-Glu (y-Pip) -Gly-Arg-pNA hydrochloride Featured
The activated factor X (FXa)-specific chromogenic substrate S-2732 is a short peptide covalently bound to pNA (4-nitroaniline). A free pNA will be cleaved off the peptide chain by activated factor X, thus enabling quantitive detection by a spectrophotometer.
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DC26055 Caspase-1/4 Chromogenic Substrate(Suc-YVAD-pNA) Featured
Suc-YVAD-pNA is a colorimetric substrate for caspase-1/interleukin-1β-converting enzyme (ICE) and caspase-4.
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DC11334 Suc-Ala-Ala-Pro-Abu-pNA trifluoroacetate salt Featured
Suc-AAP-Abu-pNA is a chromogenic peptide substrate for pancreatic elastase.It is cleaved by elastase to release p-nitroalinide (p-NA), which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
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