Novel potent and selective dual PLK1 and BRD4 inhibitor, inducing apoptosis in pediatric tumor cell lines, leading to significant tumor regression

Novel Vaccine Adjuvant for Mycobacterium tuberculosis

Novel chemically stable fluorescent marker of the ureter

Potent VMAT2 inhibitor

Selective NEP inhibitor for treatment of the symptoms of Female sexual arousal disorder (FSAD)

Selective NEP inhibitor for treatment of the symptoms of Female sexual arousal disorder (FSAD)

Novel potent human immunodeficiency virus type 1 (HIV-1) protease inhibito

Novel inhibitor of UGM, impeding C. glutamicum growth

Novel inhibitor of UGM, impeding C. glutamicum growth

Novel Nicotinic Acetylcholine Receptor Antagonist, Inhibiting Nicotine Reward and Decreases Anxiety and Decreasing Ethanol Intake in Alcohol-Preferring Rats

Novel selective delta-opioid receptor agonist

Potent and selective 11ß-HSD1 inhibitor, improving memory, including after intracerebroventricular drug administration to the central nervous system alone

Fluorescent excitatory amino acid transporter subtype 1 (EAAT1) selective inhibitor

Novel dual inhibitor of dihydrofolate reductase (DHFR) and its functional analog, Rv2671

Stereoisomer of UCN-01, inhibiting protein kinase C with a slightly reduced potency than UCN-01

Dual inhibitor of fatty acid amide hydrolase (FAAH) and α/β hydrolase domain 6 (ABHD6)

Novel potent isoprenylcysteine carboxylmethyltransferase (ICMT) inhibitor, improving survival in Ras-driven acute myeloid leukemia

Novel Agonist of the Type 1 Lysophosphatidic Acid Receptor (LPA1), Showing Efficacy in Neuropathic Pain Amelioration

The first potent nonimidazole H3 receptor antagonist (pKi=8.40)

Histamine H3 Receptor Antagonist in Treatments of Cognition Disorders

Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors

Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors

Novel non-competitive UCK2 inhibitor, suppressing nucleoside salvage in cells both in the presence and absence of DHODH inhibitors

Competitive dual inhibitor of the hydrolysis FS-3 and the phosphodiesterase substrate p-nitrophenyl thymidine 5'-monophosphate

Selective competitive inhibitor of ATX-mediated hydrolysis of the lysophospholipase substrate FS-3

Selective competitive inhibitor of ATX-mediated hydrolysis of the lysophospholipase substrate FS-3

Novel allosteric modulator of neonatal Fc receptor (FcRn), binding to the extracellular domain of FcRn

Novel inhibitor of TNF signalling by stabilising an asymmetric form of the trimer, displaying a concentration-dependent response curve and selectivity over the TNFR1 extracellular domain and control proteins

Novel inhibitor of TNF signalling by stabilising an asymmetric form of the trimer, displaying a concentration-dependent response curve and selectivity over the TNFR1 extracellular domain and control proteins

Potent ligand of synaptic vesicle protein 2A (SV2A)