Potent inhibitor of PI3 kinases

Vitamin E variant, inhibiting prostate adenocarcinoma, lung tumorigenesis, promoting thermogenic gene expression via PGC-1α upregulation, preventing methylglyoxal-induced apoptosis by reducing ROS generation and inhibiting apoptotic signaling cascades

Novel selective δ-protein kinase C inhibitor

Natural polyketide matabolite

Novel selective degrader of BCR-ABL over c-ABL in leukemia cancer cells

Iron chelating agent, chelating iron from intra-lysosomal ferritin and hemosiderin forming ferrioxamine, a water-soluble chelate excreted by the kidneys and in the feces via the bile

Deferasirox iron complex

Novel potent inhibitor of the enoyl-acyl carrier protein reductase FabI, reducing bacterial burden in mice and rescuing mice from lethal infections with clinical isolates of Acinetobacter baumannii, Klebsiella pneumoniae and E. coli

Fluorophore to myosin or actomyosin

Coumarin-caged D-luciferin, being excited in the caged group only by light of wavelength ranging within 400-430 nm

NO donor, generating a controlled release of nitric oxide in solution.

Negative control for DDR-TRK-1

Inhibitor of nonhomologous end-joining (NHEJ) DNA repair following double strand DNA breaks induced by ionizing radiation, enhancing the effects of DNA-damaging cancer drugs like etoposide, camptothecin and doxorubicin

Potent and selective DDR1 receptor tyrosine kinase inhibitor

Potent mGAT4 inhibitor

Novel Nrf2 activator

Novel NQO1 substrate, inhibiting cancer cell (NQO1-rich A549 cell line) growth

Novel Potent and Orally Bioavailable Inhibitor of the WDR5-Mixed Lineage Leukemia 1 (MLL1) Protein-Protein Interaction for the Treatment of MLL Fusion Leukemia

Novel potent blocker of mixed lineage leukemia 1 (MLL1)-WDR5 interaction, inhibiting MLL1 complex H3K4 methyltransferase activity

Novel potent and broad-spectrum antiviral agent, acting as a chain terminator for viral RNA polymerase

Potent inhibitor of Trypanosoma brucei N-myristoyltransferase (TbNMT) with markedly improved blood-brain barrier permeability

Potent potential non-opioid, non-cannabinoid analgesic for neuropathic and inflammatory pain

Novel transmission blocker of antimalarials, targeting male gametes

Novel activator of the GUS reporter activity, specific increasing in stumpy reporter gene expression

First-generation allosteric EGFR inhibitor, binding to the allosteric site of EGFR along with ATP that leads to inhibition of cell proliferation and arrest of EGFR L858R/T790M/C797S signalling

Novel selective BTK degrader, demonstrating prolonged pharmacodynamic effects

Novel Hsp90 inhibitor, exerts potent antitumor activity against HER2-positive breast cancer through disruption of Hsp90-Cdc37 interaction

Novel potent and selective TEAD autopalmitoylation inhibitor, inhibiting TEADs transcription activity and downstream gene expression

Novel, Potent and Selective Histone Methyltransferase SET7 Inhibitor

Novel, Potent and Selective Histone Methyltransferase SET7 Inhibitor