Non-steroidal selective modulator for the glucocorticoid receptor (GR)

Potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist

Cell-permeable Akt1/2 inhibitor with improved solubility and Ak2 selectivity

Novel potent and selective aldo-keto reductase 1C3 inhibitor, displaying selectivity for AKR1C3 over other AKR1C enzymes and COX

Novel S1P1 agonist

Novel inhibitor of p38 MAP kinase

Novel Inhibitor of EGF-EGFR Interactions

Novel and potent PAK1 (p21-activated kinase 1) inhibitor, suppressing the proliferation of human gastric cancer cells significantly by downregulation of PAK1-NFκB-CyclinB1 pathway

Novel antiproliferative agent

Novel protein kinase C (PKC) activator, preferentially binding to the novel PKC isoforms PKCδ and PKC∈, stimulated a striking preferential redistribution of PKC∈ to the plasma membrane relative to PKCα, inducing major changes in cytoskeletal reorganizatio

Novel β3-Adrenoceptor agonist, reducing body fat in obese beagles

Novel inhibitor of long chain fatty acid elongase 6 (ELOVL6)

Novel FMS-like tyrosine kinase 3 (FLT3) inhibitor, showing improved anti-leukemic efficacy in FLT3-ITD-positive AML cells, specifically inhibiting cell growth and apoptotic death, down-regulating DNA repair genes involved in homologous recombination and n

Novel quorum sensing (QS) signaling molecule produced by Staphylococcus aureusagr type IV

Natural selective inhibitor of IKKα/β by covalently binding a conserved cysteine

Microtubule>Tubulin polymerization inhibitor with marked antitumor activities

Natural inhibitor of Xanthomonas oryzae growth, against rice pathogens

Novel Keap1-Nrf2 pathway activator by inhibiting the Keap1 protein

Novel Keap1-Nrf2 pathway activator by inhibiting the Keap1 protein

Inhibitor of tryptophan hydroxylase activation

alpha Adrenoceptor agonist for the treatment of neuropathic pain

Inhibitor of the basal proton conductance of UCP1; Retinoid, displaying a nonspecific stimulation of NADH oxidation in control mitochondria

Novel potent and specific RARα antagonist

Retinoic Acid Receptor α Subtype Specific Agonist

Novel potent and selective RARα inhibitor

Novel methionine adenosyltransferase 2A (MATA2 ) inhibitor

Novel inducer of anti-tumor immunity, converting tumors into in situ autologous vaccines

Inhibitor of NS2B-NS3 proteases of the Dengue virus serotypes 2 and 3

Anticancer agent with antioxidant and chemopreventive properties

Novel potent FKBP12 ligand