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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC71858 | Ex26 |
Ex26 (S1P1-IN-Ex26) is a potent and selective Sphingosine 1-phosphate receptor 1 (S1P1) antagonist (IC50=0.93 nM). Ex26 shows >3,000-fold selectivity for S1P1 over other Sphingosine 1-phosphate receptors. Ex26 can be used in experimental autoimmune encephalomyelitis reseach.
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| DC71857 | Euphoscopin C |
Euphoscopin C is a diterpenoid found in Euphorbia helioscopia. Euphoscopin C can significantly enhance the killing activity of NK cells against H1299 -luci cells and A549-luci cells.
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| DC71856 | Etedesiran |
Etedesiran is a Myotonin-protein kinase (MT-PK, MDPK, or DMPK) inhibitor.
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| DC71855 | Epirosmanol |
Epirosmanol is a nature diterpene lactone from S. officinalis. Epirosmanol shows anti-cancer activity and inhibits melanin biosynthesis against melanoma cells. Epirosmanol also exhibits DPPH radical scavenging activity.
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| DC71854 | DMT-5Me-dC(Bz)-CE Phosphoramidite |
DMT-5Me-dC(Bz)-CE Phosphoramidite is used in the preparation of locked nucleic acids (LNAs) for optimization of fluorescent oligonucleotide probes with improved spectral properties and target binding.
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| DC71853 | DM-Nitrophen tertasodium |
DM-Nitrophen tertasodium is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light. DM-Nitrophen tertasodium can be used for study of Ca2+ signaling.
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| DC71852 | DM-Nitrophen |
DM-Nitrophen is a Ca2+ cage. DM-Nitrophen releases Ca2+ when cleaved upon illumination with near-ultraviolet light.
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| DC71851 | DIBAC-GGFG-NH2CH2-Dxd |
DIBAC-GGFG-NH2CH2-Dxd (compound LP4), a Camptothecin derivative, is a linker-payload of protein-drug conjugates.
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| DC71850 | DB772 hydrate |
DB772 hydrate is a bovine viral diarrhoea virus (BVDV) inhibitor. DB772 also has anti-prion activity.
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| DC71849 | Colestilan |
Colestilan (MCI-196) is a non-absorbed, non-calcium-based phosphate binder and is also a non-metallic, anion exchange resin. Colestilan is orally active and can be used for hypercholesterolaemia research.
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| DC71848 | Cedazuridine hydrochloride |
Cedazuridine (E7727) (Compound 7a) hydrochloride is an orally active cytidine deaminase (CDA) inhibitor with an IC50 value of 0.4 μM. Cedazuridine hydrochloride can be used for cancer research.
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| DC71846 | Bocconoline |
Bocconoline is a potent early endosome antigen 1 (EEA1) inhibitor. Bocconoline can be isolated from Macleaya cordata. Bocconoline can be used for the research of Parkinson’s disease (PD).
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| DC71845 | Berberine ursodeoxycholate |
Berberine ursodeoxycholate (HTD1801), an ionic salt of Berberine and Ursodeoxycholic acid, is an orally active and potent hypolipidemic agent. Berberine ursodeoxycholate shows significantly great reduction in liver fat content. Berberine ursodeoxycholate has a broad spectrum of metabolic activity. Berberine ursodeoxycholate can be used for the research of hyperlipidemia, non-alcoholic steatohepatitis (NASH) and diabetes.
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| DC71844 | Belatacept |
Belatacept (BMS 224818) is a selective T-cell costimulation blocker. Belatacept binds to CD 80/86 ligands and thereby inhibits the CD-28-mediated T-cell costimulation. Belatacept can be used in the research of Immunosuppression in organ transplants.
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| DC71842 | AS1134900 |
AS1134900 is a highly selective, allosteric and uncompetitive NADP+-dependent malic enzyme 1 (ME1) inhibitor.
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| DC71841 | Acifluorfen-methyl |
Acifluorfen-methyl is an inhibitor of the heme and chlorophyll biosynthetic enzyme protoporphyrinogen oxidase (Protox). Acifluorfen-methyl is a photobleaching herbicide.
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| DC71840 | 5-(3-Hydroxybenzylidene)-rhodanine |
5-(3-Hydroxybenzylidene)-rhodanine, a derivative of rhodanine, can be used as an algicidal agent.
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| DC71839 | 1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium |
Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) is a modified PS product generated following activation of the NADPH oxidase and lyso-PS signaling. Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium through the macrophage G2A functions to enhance existing receptor/ligand systems for resolution of neutrophilic inflammation.
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| DC71838 | 1H-1-Ethyl Candesartan Cilexetil |
1H-1-Ethyl Candesartan Cilexetil is a potential impurity found in bulk preparations of Candesartan Cilexetil.
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| DC71837 | 16-Azidohexadecanoic acid |
16-Azidohexadecanoic acid, a synthetic fatty acid, can be used as a modification marker for nucleotides and a molecular probe for fatty acid metabolism.
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| DC71834 | (R)-FL118 |
(R)-FL118 (10,11-(Methylenedioxy)-20(R)-camptothecin) is the R-enantiomer of FL118. (R)-FL118 shows anticancer activity.
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| DC71833 | (1R,2S)-Xeruborbactam disodium |
(1R,2S)-Xeruborbactam ((1R,2S)-QPX7728) disodium is a boronic acid derivative.
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| DC70252 | BI-4924 Featured |
BI-4924 (BI 4924) is a potent, selective NADH/NAD+-competitive PHGDH inhibitor with IC50 of 2 nM.BI-4924 splays high selectivity against the majority of other dehydrogenase targets.
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| DC23954 | ISO-1 Featured |
ISO-1 is a macrophage migration inhibitory factor (MIF) antagonist with an IC50 of 7 μM.
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| DC71701 | Elosulfase alfa |
Elosulfase alfa (BMN 110) is a recombinant form of human N-acetylgalactosamine-6-sulfatase (GALNS). Elosulfase alfa is used as an enzyme replacement therapy for mucopolysaccharidosis IVA (MPS IVA), also known as Morquio A syndrome.
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| DC71700 | Lumogallion |
Lumogallion is a highly sensitive fluorescent reagent for the detection of aluminum, gallium and other metals. Lumogallion has an excitation wavelength of 490 nm and an emission spectrum in the range of 520 nm to 650 nm, with a peak near 580 nm.
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| DC71696 | Palmitoyloleoylphosphatidylglycerol |
Palmitoyloleoylphosphatidylglycerol is an anionic surfactant lipid. Palmitoyloleoylphosphatidylglycerol suppresses Der p 2-stimulated inflammatory responses in lung epithelial cells and macrophages.
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| DC71694 | Diphenyl-1-pyrenylphosphine |
Diphenyl-1-pyrenylphosphine (DPPP) is a fluoregenic peroxide reactive probe. Diphenyl-1-pyrenylphosphine exhibits a unique phototriggered aggregation-induced emission (AIE)/aggregation-induced quenching (ACQ) transition with a remarkable third-order nonlinear optical signal change.
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| DC71685 | Dioleoylphosphatidylglycerol |
Dioleoylphosphatidylglycerol (DOPG) is a naturally occurring phospholipid that can be produced by the combined action of aquaporin 3 (AQP3) and phospholipase D2 (PLD2). Dioleoylphosphatidylglycerol inhibits macrophage inflammatory mediator production in response to heat shock protein B4 (HSPB4) activation of toll-like receptor 2 (TLR2) .
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| DC71684 | TM-1 |
TM-1 is a potent inhibitor of pyruvate dehydrogenase kinase (PDHK1). TM-1 inhibits PDHK1 and PDHK2 with IC50s of 2.97 μM and 5.2 μM, respectively. TM-1 blocks pyruvate dehydrogenase complex (PDHC) phosphorylation, and inhibits cell proliferation.
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