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Cat. No. Product Name Field of Application Chemical Structure
DC71670 KR-39038
KR-39038 is an orally active and potent GRK5 (G protein-coupled receptor kinase 5) inhibitor, with an IC50 of 0.02 μM. KR-39038 significantly inhibits angiotensin II-induced cellular hypertrophy through suppression of HDAC5 pathway in neonatal cardiomyocytes. KR-39038 shows profound anti-hypertrophic effects and improved cardiac function. KR-39038 can be used for heart failure research.
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DC71660 K027
K027 is a potent reactivator of Organophosphates (OP)-inhibited acetylcholinesterase (AChE). K027 can be used for the research of Alzheimer's disease.
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DC71654 WAY-297848
WAY-297848 is a novel glucokinase activator with potential use as a drug for the prevention or treatment of hyperglycemia, diabetes, obesity, dyslipidemia, metabolic syndrome, etc.
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DC71640 (-)Clausenamide
(-)Clausenamide is an active alkaloid isolated from the leaves of Clausena lansium (Lour.) Skeels, and improves cognitive function in both normal physiological and pathological conditions. (-)Clausenamide inhibits β-amyloid (Aβ) toxicity, blocking neurofibrillary tangle formation by inhibiting the phosphorylation of tau protein.
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DC71611 TFMU-ADPr
TFMU-ADPr is a general substrate for monitoring poly(ADP-ribose) glycohydrolase (PARG) activity. TFMU-ADPr can directly report on total PAR hydrolase activity via release of a fluorophore. TFMU-ADPr has excellent reactivity, generality, stability, and usability. TFMU-ADPr is a versatile tool for assessing small-molecule inhibitors in vitro and probing the regulation of ADP-ribosyl catabolic enzymes.
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DC71610 11-Mercaptoundecanoic acid
11-Mercaptoundecanoic acid (MUA) is a thiol-containing fatty acid, which has been described in the preparation of self-assembled monolayers (SAMs), mixed monolayers, and metal-associated nanoparticles.
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DC71609 Endoxifen E-isomer
Endoxifen E-isomer (E-Endoxifen), an E-isomer of Endoxifen and impurity in Endoxifen Z-isomer drug substance, exhibits antiestrogenic effects.
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DC71607 p-Nitrobenzyl mesylate
p-Nitrobenzyl mesylate is an alkylating reagent for direct kinase substrate identification.
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DC71604 PNU-282987 S enantiomer free base
PNU-282987 S enantiomer free base is the S-enantiomer of PNU-282987 free base, which is an α7 nicotinic acetylcholine receptor (α7 nAChR) agonist.
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DC71603 FSG67
FSG67 is a glycerol 3-phosphate acyltransferase (GPAT) inhibitor with an IC50 of 24 μM.
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DC71602 Fmoc-Lys(5-FITC)-OH
Fmoc-Lys(5-FITC)-OH is a building block for in-sequence Lys labeling by FITC. FITC can be used to label peptides or proteins.
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DC71601 GEMSA
GEMSA is a potent inhibitor of enkephalin convertase (Ki=8.8 nM). GEMSA elicites analgesia.
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DC71600 Milrinone lactate
Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock.
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DC71599 Lutropin
Lutropin is a heterodimeric glycoprotein, a hormone produced by gonadotropic cells in the anterior pituitary gland, also known as luteinizing hormone and lutrophin. Lutropin stimulates follicular development, and can be used for researching infertility.
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DC71598 Reteplase
Reteplase (BM 06.022) is a recombinant plasminogen activator, consists of the kringle 2 and protease domains of human tissue-type plasminogen activator. Reteplase is a t-PA mutant produced in Escherichia coli by DNA technology, and is unglycosylated.
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DC71597 Turoctocog alfa
Turoctocog alfa is a recombinant coagulation factor VIII (FVIII) from chinese hamster ovary (CHO) cells. Turoctocog alfa can be used for researching haemophilia A.
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DC71596 Octocog alfa
Octocog alfa is a second-generation full-length recombinant factor VIII, as a antihemophilic factor.
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DC71595 Ezurpimtrostat hydrochloride
Ezurpimtrostat hydrochloride (compound 2-3) is a potent and orally active anti-fibrotic agent. Ezurpimtrostat hydrochloride reduces significantly the liver fibrosis in DEN (diethyl nitrosamine) cirrhotic rat model. Ezurpimtrostat hydrochloride can be used for the research of fibrosis, cancer, autophagy and cathepsins B (CTSB), L (CTSL) and D (CTSD) related diseases .
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DC71594 Acloproxalap
Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, organ diseases, and viral infection-related syndromes.
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DC71593 15:0-18:1-15:0 TG-d5
15:0-18:1-15:0 TG-d5 is deuterium labeled 15:0-18:1-15:0 TG.
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DC71592 C15 Ceramide-1-phosphate-d7
C15 Ceramide-1-phosphate-d7 is deuterium labeled C15 Ceramide-1-phosphate.
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DC71591 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 sodium
1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine-d5 (sodium) is deuterium labeled 1-Heptadecanoyl-2-eicosatrienoyl-sn-glycero-3-phospho- L-serine (sodium).
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DC71589 Brogidirsen
Brogidirsen exerts the stimulatory function of synthesis of functional dystrophin.
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DC71587 Nifuraldezone-15N3
Nifuraldezone-15N3 is the 15N3 labeled Nifuraldezone.
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DC71586 (R)-GNE-274
(R)-GNE-274 is a enantiomer of GNE-274. GNE-274 is a non-degrader that is structurally related to GDC-0927 (estrogen receptor degrader).
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DC71585 Tazide
Tazide is an antineoplastic agent.
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DC71584 Opadotina
Opadotina is a small molecule of anvatabart opadotin. Opadotina shows antineoplastic activity.
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DC71583 Fosimdesonide
Fosimdesonide, a small molecule of adalimumab fosimdesonide, is a potent immunomodulator. Fosimdesonide shows anti-inflammatory activity.
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DC71582 Lafadofensine (D-(-)-Mandelic acid)
Lafadofensine D-(-)-Mandelic acid is the monoamines reuptake inhibitor. Lafadofensine D-(-)-Mandelic acid has sufficient effects after short-term administration.
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DC71581 N-Butylfluorescein
N-Butylfluorescein is an alkyl-substituted fluorescein, can be used for synthesis of fluorogenic substrates for assaying phosphatidylinositol-specific phospholipase C.
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