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Cat. No. Product Name Field of Application Chemical Structure
DC71576 β-S-ARCA
β-S-ARCA is a mRNA 7-methylguanosine (m7G) cap analog carrying a phosphorothioate (PS) moiety. mRNAs incorporating β-S-ARCA have elongated cellular half-lives and showed augmented protein expression. β-S-ARCA D1 has been applied in researching experimental mRNA-based anticancer vaccines.
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DC71575 5,5'-Difluoro BAPTA
5,5'-Difluoro BAPTA is the most widely used probe for studying cytosolic free Ca2+ by 19F NMR. 5,5'-Difluoro BAPTA has high selectivity for Ca2+. 5,5'-Difluoro BAPTA can inhibit the growth of pollen tube.
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DC71574 NHS-SS-Ac
NHS-SS-Ac is an amine-reactive product synthesized from acetic acid.
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DC71573 Insulin lispro
Insulin lispro is a recombinant human insulin analogue and is one of three rapid-acting insulin analogues available. Insulin lispro can be used for the research of hyperglycaemia in diabetes mellitus.
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DC71572 Bodipy 8-chloromethane
BODIPY-8-chloromethane is a fluorophore. BODIPY-8-chloromethane can be used as as a fluorescent probe.
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DC71571 Fluorescein octadecyl ester
Fluorescein octadecyl ester is a lipophilic fluorescent reagent is immobilized in a plasticized PVC membrane. Fluorescein octadecyl ester can reversibly recognize alcohol molecules and can be used to determine the concentration of ethanol in alcoholic drinks. Fluorescein octadecyl ester can be used as acceptor to make optrode membrane for the determination of picric acid.
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DC71570 Exo2
Exo2 is a secretion inhibitor. Exo2 perturbs trafficking of Shiga toxin between endosomes and the trans-Golgi network. Exo2 blocks secretory cargo exit from the ER (endoplasmic reticulum) and disrupts the Golgi apparatus, but does not affect the morphology of the TGN (trans-Golgi network) Exo2 can stimulate calcium-dependent exocytosis in permeabilized adrenal chromaff in cells.
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DC71569 2-Nitrophenanthraquinone
2-Nitrophenanthraquinone is a bioactive compound.
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DC71568 Epitizide
Epitizide, a benzothiadiazine, commonly found in combination Triamterene, is used to produce diuresis.
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DC10799 SSR-240612 HCl Featured
SSR-240612 is a bradykinin B1 receptor antagonist potentially for the treatment of chronic pain.
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DC34272 SPP-86 Featured
SPP-86 is a potent RET inhibitor.
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DC22213 Ro 60-0175 Featured
Ro 60-0175 is a potent, selective 5-HT2C receptor agonist with pKi of 9, 7.5, 5.4, 5.2 and 5.6 for human 5-HT2C, 2A, 1A, 6 and 7 receptors respectively.
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DC32099 Ro 16-6028 Featured
Bretazenil, also known as Ro 16-6028, is GABA A receptor agonist potentially for the treatment of anxiety disorders. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5 and α6 subunit containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.
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DC71188 GSK329 Featured
GSK329 is a potent and selective diarylurea inhibitor of the cardiac-specific kinase TNNI3K. GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.
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DC34253 CAY10444 Featured
CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors[1].
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DC46153 (±)-ErSO Featured
(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator.
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DC11313 NSC 146109 (hydrochloride) Featured
NSC 146109 is an activator of the tumor suppressor p53 that increases expression of p53 and the p53 target DR5 in wild-type and p53-knockout HCT116 colon adenocarcinoma cells.
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DC20111 Kira8 Featured
Kira8 is a mono-selective IRE1α inhibitor that allosterically attenuates IRE1α’s RNase.
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DC33149 JT010 Featured
JT010 is a potent agonist of TRPA1 with an EC50 of 0.65 nM.
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DC71460 SBI-581
SBI-581 is an orally active and potent selective serine-threonine kinase TAO3 inhibitor, with an IC50 of 42 nM. SBI-581 promotes TKS5α accumulation at RAB11-positive vesicles. SBI-581 inhibits invadopodia formation. SBI-581 shows reasonable pharmacokinetics in mice using IP injection. SBI-581 shows antitumor activity.
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DC71459 SQM-NBD
SQM-NBD is a potent and selectiveAIE fluorescent probe. SQM-NBD exhibits excellent sensitivity to Cys and Hcy with the LOD of 54 nM and 72 nM, respectively.SQM-NBD has good cell permeability and low cytotoxicity. SQM-NBD has the potential for Cys/Hcy identification under physiological and pathological conditions.
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DC71458 Campneoside II
Campneoside II is a compound isolated from Paulownia tomentosa var. tomentosa wood. Campneoside II exhibits excellent anti-complement activity.
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DC71457 Iopentol
Iopentol is a non-ionic, intravascular contrast media.
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DC71456 INI-43
INI-43, a Kpnβ1 inhibitor, interferes with the nuclear localization of Kpnβ1 and known Kpnβ1 cargoes, NFAT, NFκB, AP-1 and NFY.
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DC71455 Dieckol
Dieckol, is a naturally occurring phlorotannin found in some brown algal species. Dieckol has anti-bacterial, anti-cancer, anti-oxidant, anti-aging, anti-diabetic, neuroprotective actions.
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DC71454 Obovatol
Obovatol is a biphenyl ether lignan isolated from the leaves of Magnolia obovata Thunb.
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DC71453 Verrucosin
Verrucosin (Compound 3) is a compound isolated from Myristica fragrans.
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DC71452 Ornoprostil
Ornoprostil is a prostaglandin E1 analogue. Ornoprostil is orally active and can be used for gastric ulcer research.
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DC71451 Primulic acid I
Primulic acid I (Primulasaponin 1) is a plant-derived triterpenoid saponin with one sugar chain (monodesmoid).
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DC71450 Cararosinol A
Cararosinol A is a compound isolated from the roots of Caragana sinica.
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