Selective beta-1 adrenergic receptor antagonist with antihypertensive and anti-glaucoma activities and devoid of intrinsic sympathomimetic activity

Natural antibiofilm agent and adjuvant on the antifungal therapy related to resistant infections caused by C. glabrata

Phytoestrogen, possessing typical curare-like action

Potent ligand of the serotonin (5-HT) and dopamine (DA) transporters used in diagonisis of Parkinson's disease as SPECT imaging precursor

Novel negative allosteric modulator of the ß2-adrenergic receptor (ß2AR), inhibiting cAMP production through the ß2AR, but not that mediated by other Gs-coupled receptors, also inhibiting ß-arrestin recruitment to the activated ß2AR

Novel selective inhibitor of plasma kallikrein, blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE

Novel inhibitor of plasma kallikrein

Novel antibacterial agent against multidrug-resistant Escherichia coli at low concentrations as 0.007 mM, disintegrating membrane, accelerating ROS accumulation, reducing bacterial metabolism, and intercalating into DNA groove

Novel antibacterial agent against multidrug-resistant Escherichia coli at low concentrations as 0.007 mM, disintegrating membrane, accelerating ROS accumulation, reducing bacterial metabolism, and intercalating into DNA groove

Long-acting calcium-blocking agent with significant anti-anginal activity

Useful pharmaceutical building block

Anorectic, primarily promoting weight loss through reduced appetite

Inhibitor of 4-hydroxyphenylpyruvate dioxygenase (HPPD), acting as a herbicide

anti-HSV agent

Potent D2/D4 dopamine receptor antagonist, neuroleptic and antipsychotic

Antiandrogen, being effective in the treatment of acne, seborrhea, and hirsutism in women

Irreversible and nonselective Monoamine_oxidase_inhibitor>monoamine oxidase inhibitor (MAOI)

Novel inhibitor of HIV-1 Rev function, also acting as a cytostatic agent with substantial antiretroviral activity

Novel potent PI3K inhibitor, suppressing metastasis of non-small cell lung cancer cells by modulating β-catenin/ZEB1 regulatory loop, blocking AKT phosphorylation

Inhibitor of angiotensin-converting enzyme (ACE); Prodrug of benazeprilat

Inhibitor of monoamine oxidase; Anti-serotonin agent

Novel potent and specific inhibitor of dog gastric lipase (DGL)

Fatty Ester for Lipid Research

Active metabolite of beclomethasone dipropionate

Novel CBP/p300 Bromodomains inhibitor, binding BRD4 almost identical to SGC-CBP30

Novel specific bona fide EthR-inhibitor, boosting ETH 4 times in an intravenously infected TB mice model

Novel EthR inhibitor and ethionamide booster

Novel activator of ethionamide

Novel EthR inhibitor, boosting antituberculous activity of ethionamide

Potent and selective hydroxamate PfAM1 inhibitor