SR 8278|SR8278|CAS 1254944-66-5

Cas No.:	1254944-66-5
Chemical Name:	1,2,3,4-Tetrahydro-2-[[5-(methylthio)-2-thienyl]carbonyl]-3-isoquinolinecarboxylic acid ethyl ester
Synonyms:	SR8278,SR-8278，SR 8278
SMILES:	O=C(OCC)C1N(C(C2=CC=C(SC)S2)=O)CC3=CC=CC=C3C1
Formula:	C₁₈H₁₉NO₃S₂
M.Wt:	361.48
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. SR8278 inhibits the REV-ERBα transcriptional repression activity with an EC50 of 0.47μM. SR8278 is used to regulate the metabolism in organisms and study biological rhythm[1][2].

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