ML353 (VU0478006)|DC Chemicals

Cas No.:
Chemical Name:	ML353 (VU0478006)
Synonyms:	ML-353; ML 353; VU0478006; VU 0478006; VU-0478006,3-Azabicyclo[3.1.0]hexan-3-yl-[5-[2-(3-fluorophenyl)ethynyl]pyridin-2-yl]methanone
SMILES:	CC1=NN=C2N1C(SC(C)=C3C)=C3C(C4=CC=C(Cl)C=C4)=N[C@H]2CC(NC5=CC=C(OCCOCCOCCOCCNC6=C(C(N(C7CCC(NC7=O)=O)C8=O)=O)C8=CC=C6)C=C5)=O
Formula:	C₁₉H₁₅FN₂O
M.Wt:	306.33
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication:	1) Karen J. Gregory et al., Identification of a high affinity MPEP-site silent allosteric modulator (SAM) for the metabotropic glutamate subtype 5 receptor (mGlu5); Probe Reports from the NIH Molecular Libraries Program 2010 2) Zoltán Orgován et al. Allosteric Molecular Switches in Metabotropic Glutamate Receptors, Chemistry Europe, (2020). doi.org/10.1002/cmdc.202000444

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