Simvastatin sodium | HMG-CoA Inhibitor

Cas No.:	101314-97-0
Chemical Name:	Simvastatin hydroxy acid sodium salt
Synonyms:	Simvastatin hydroxy acid sodium salt;Simvastatin (sodium salt);Simvastatin sodium;Simvastati;SIMVASTATIN, SODIUM SALT;FYSMQCWXGBXWLB-VMCZNHHFSA-M;Simvastatin Impurity as Sodium Salt;Simvastatin EP Impurity A Sodium Salt;SiMvastatin IMp. A (EP) as SodiuM Salt;Sodium (3R,5R)-7-{(1S,2S,6R,8S,8aR)-8-[(2,2-dimethylbutanoyl)oxy]-2,6-dimethyl-1,2,6,7,8,8a-hexahydro-1-naphthalenyl}-3,5-dihydroxyheptanoate;IMp. A (EP) as SodiuM Salt: (3R,5R)-7-[(1S,2S,6R,8S,8aR)-8-[(2,2-DiMethylbutanoyl)oxy]-2,6-diMethyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid SodiuM Salt (Tenivastatin SodiuM Salt;Simvastatin hydroxy acid sodium
SMILES:	CCC(C)(C)C(O[C@@H]1C2[C@H]([C@@H](C)C=CC2=C[C@H](C)C1)CCC(O)C[C@@H](O)CC([O-])=O)=O.[NaH]
Formula:	C₂₅H₄₀NaO₆
M.Wt:	459.571279525757
Purity:	>99%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC28572	Cerivastatin	Cerivastatin is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin reduces low-density lipoprotein cholesterol levels. Cerivastatin also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect.
DC28349	Simvastatin sodium	Simvastatin sodium is a lactone prodrug, can be hydrolysed to active hydroxy-acid by non-specific carboxyesterases or non-enzymatic processes. Simvastatin sodium shows a inhibition of HMG-CoA reductase with a Ki value of 0.12 nM.