rac BHFF|cas 123557-91-5

Cas No.:	123557-91-5
Chemical Name:	racBHFF，rac-BHFF，rac BHFF
Synonyms:	racBHFF，rac-BHFF，rac BHFF
SMILES:	CC(C)(C)C1=CC(=C2C(=C1)C(C(=O)O2)(C(F)(F)F)O)C(C)(C)C
Formula:	C₁₇H₂₁F₃O₃
M.Wt:	330.34
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

rac-BHFF is a potent and orally active allosteric enhancer of GABAB receptor[1].

In Vivo:

rac-BHFF has anxiolytic-like properties in stress-induced hyperthermia (SIH) in mice[1]. rac-BHFF (3, 10, 30 and 100 mg/kg, p.o.) reverses SIH and high significance was reached for 100 mg kg−1 (P<0.001)[1]. Animal Model: Male NMRI mice (20-25 g)[1]. Dosage: 3, 10, 30 or 100 mg/kg. Administration: P.O.. Result: Significantly increased the LRR effects of a subthreshold dose of baclofen at doses of 3 mg/kg and above.

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