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Other Targets

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Cat. No. Product Name Field of Application Chemical Structure
DC36047 beta-Amyrin
beta-Amyrin is a molecule which has been shown to exhibit long-lasting antinociceptive and anti-inflammatory properties. beta-Amyrin activates cannabinoid receptors CB1 and CB2 and inhibits the production of cytokines and expression of NF-κB, CREB and cyclooxygenase 2.
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DC36046 Ambazone
Ambazone is an antiseptic agent with potential antibacterial and antileukemic activity. Although the exact mechanism of action remains unclear, ambazone appears to interfere with the membrane-bound nucleotide system by increasing the intracellular concentration of cAMP in leukemia cells and macrophages, which potentially contributes to this agent's antineoplastic activity.
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DC36035 Aloperine
Aloperine is an alkaloid with diverse biological activities including antiviral, anticancer, antioxidant, and anti-inflammatory actions. It inhibits HIV-1 replication and envelope-mediated cell-cell fusion in vitro. Aloperine also inhibits the growth of HL-60, U937, and K562 leukemia cell lines.
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DC36033 Tiropramide hydrochloride
Tiropramide hydrochloride is a smooth muscle antispasmodic agent which has been shown to to have some efficacy in normalizing intestinal transit time and in inducing symptomatic relief for Irritable Bowel Syndrome (IBS) patients.
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DC36003 Thiol-PEG3-alcohol
Thiol-PEG3-alcohol is a PEG derivative containing a thiol group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC36001 Thiol-PEG4-t-butyl ester
Thiol-PEG4-t-butyl ester is a PEG derivative containing a thiol group and a t-butyl ester. The hydrophilic PEG spacer increases solubility in aqueous media. The thiol group reacts with maleimide, OPSS, vinylsulfone and transition metal surfaces including gold, silver, etc. The t-butyl protected carboxyl group can be deprotected under acidic conditions.
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DC35959 Ms-PEG5-Ms
Ms-PEG5-Ms is a PEG Linker.
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DC35938 Tos-PEG5-t-butyl ester
Tos-PEG5-t-butyl ester is a PEG derivative containing a t-butyl ester and a tosyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The tosyl group is a very good leaving group for nucleophilic substitution reactions.
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DC35841 5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid
5-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)pentanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35840 4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid
4-(2,5-dioxo-2H-pyrrol-1(5H)-yl)butanoic acid contains a maleimide group and a terminal carboxylic acid. The terminal carboxylic acid can be reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.
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DC35483 Heptaethylene glycol
Heptaethylene glycol is a PEG Linker.
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DC35234 3-(2-bromoacetamido)propanoic acid NHS ester
3-(2-bromoacetamido)propanoic acid NHS ester is a PEG derivative containing a bromide group and an NHS ester. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules.
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DC35222 Bromo-PEG4-bromide
Bromo-PEG4-bromide is a PEG derivative containing two bromide groups. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
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DC35211 Bromo-PEG3-alcohol
Bromo-PEG3-alcohol is a PEG derivative containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35210 Bromo-PEG2-alcohol
Bromo-PEG2-alcohol is a PEG derivative containing a bromide group and a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups.
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DC35021 Benzyl-PEG6-alcohol
Benzyl-PEG6-alcohol is a Benzyl PEG Linker. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34979 Aminooxy-PEG2-methane
Aminooxy-PEG2-methane is a PEG derivative containing an aminooxy group and a methane group. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. PEG Linkers may be useful in the development of antibody drug conjugates and drug delivery methods.
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DC34931 m-PEG5-amine
m-PEG5-amine is a PEG derivative containing an amino group. The amine group is reactive with carboxylic acids, activated NHS esters, carbonyls (ketone, aldehyde) etc. PEG Linkers may be useful in the development of antibody drug conjugates.
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DC34772 Propargyl-PEG1-acid
Propargyl-PEG1-acid is a PEG derivative containing a propargyl group with a terminal carboxylic acid. The terminal carboxylic acid can reacted with primary amine groups in the presence of activators (e.g. EDC, or DCC) to form a stable amide bond. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.
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DC34755 DCC Crosslinker
DCC Crosslinker, N,N'-dicyclohexylcarbodiimide, is a zero-length crosslinker that is often employed in peptide synthesis and organic synthesis. DCC's carbodiimide is useful for coupling amines and carboxylates without the insertion of spacer atoms. DCC crosslinker is commonly used in the synthesis of active ester-containing reagents.
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DC34747 DSP Crosslinker
DSP Crosslinker, also known as DTSSP Crosslinker, is a homobifunctional and cleavable crosslinker that is cell membrane permeable. DSP crosslinker has amine-reactive N-hydroxysuccinimide (NHS) esters at both ends of a cleavable, 8-atom (12.0 angstrom) spacer arm, and DSP cross links occur via these NHS esters.
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DC34723 NSC 10441
Acid Orange 6 is an orange dye.
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DC34704 Acexamic acid
Acexamic acid is wound-healing agent and analgesic composed of plasmutan. Acexamic acid is used to avoid pulmonary fibrosis in adult respiratory distress syndrome, but may cause complications including hypercalcemia and hypernatremia.
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DC34690 Sulfaguanidine
Sulfaguanidine is a sulfanilamide antimicrobial agent that is used to treat enteric infections. It functions by blocking the production of folic acid, to act as an antibiotic. It is active against Gram positive bacteria and Gram negative bacteria.
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DC34685 Parathion
Parathion is a highly toxic cholinesterase inhibitor that is used as an acaricide and as an insecticide.
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DC34670 TEPA
TEPA is an insect chemosterilant and an antineoplastic agent. It inhibits carcinoma growth.
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DC34669 Furalaxyl
Furalaxyl is an acylamino chiral fungicide.
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DC34668 Sulfacarbamide
Sulfacarbamide is an antimicrobial agent that has been investigated as a therapeutic biochemical for diabetes treatment. It may lower blood sugar.
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DC34664 Zimelidine
Zimelidine is a serotonin uptake inhibitor formerly used for depression, but was withdrawn worldwide because of the risk of Gullain-Barre syndrome associated with its use.
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DC34663 Narasin
Narasin is a novel agent that inhibits dengue virus replication in vitro through non-cytotoxic mechanisms, thus indicating its potential to be further developed as a therapeutic agent.It is used for the treatment of coccidiosis from a class of protozoa. It also triggers phospholipid scrambling of the erythrocyte cell membrane, an effect partially dependent on Ca2+ entry. It has been shown to foster apoptosis of tumor cells.
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