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| A028 | Alemtuzumab Featured |
Alemtuzumab is a humanized monoclonal antibody specific to lymphocyte antigens. It is a recombinant DNA-derived humanized monoclonal antibody (Campath-1H) that is directed against the 21-28 kD cell surface glycoprotein,CD52. The Campath-1H antibody is an IgG1 kappa with human variable framework and constant regions, and complementarity-determining regions from a murine (rat) monoclonal antibody (Campath-1G). Campath is produced in mammalian cell (Chinese hamster ovary) suspension culture in a medium containing neomycin.
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| A027 | Panitumumab Featured |
Panitumumab, formerly ABX-EGF, is a fully human monoclonal antibody specific to the epidermal growth factor receptor (also known as EGF receptor, EGFR, ErbB-1 and HER1 in humans).
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| A024 | Pertuzumab Featured |
Pertuzumab, a humanized monoclonal antibody, is a HER2 dimerization inhibitor for the treatment of metastatic HER2-positive breast cancer.
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| A025 | Natalizumab Featured |
Natalizumab is a recombinant, humanized monoclonal antibody, binds to α4β1-integrin and blocks its interaction with vascular cell adhesion molecule-1 (VCAM-1). Natalizumab can be used for the treatment of relapsing remitting multiple sclerosis and Crohn's disease. Natalizumab is also the first targeted therapy which blocks an essential mechanism for lymphocyte entry to the CNS and thus prevents acute demyelinating relapses.
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| A023 | Vedolizumab Featured |
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of ulcerative colitis and Crohn's disease.
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| A022 | Ustekinumab Featured |
Ustekinumab is human monoclonal antibody to a polypeptide found on interleukin-12 and -23 that is used to treat autoimmune conditions and is approved for use in severe psoriasis.
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| A021 | Trastuzumab Featured |
Trastuzumab (anti-human HER2) is a humanized, recombinant monoclonal antibody that binds to the extracellular domain of HER2.
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| A018 | Rituximab Featured |
Rituximab (anti-CD20) is a chimeric anti-CD20 mAb that binds the CD20 antigen on B cells with a binding affinity of 5 nM,
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| A017 | Ramucirumab Featured |
Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors. Ramucirumab is a recombinant human immunoglobulin G1 monoclonal antibody that binds to the extracellular binding domain of VEGFR-2 and prevents the binding of VEGFR ligands: VEGF
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| A013 | Ipilimumab Featured |
Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor.
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| A012 | Infliximab Featured |
Infliximab is a tumor necrosis factor TNF-α blocker and a chimeric monoclonal IgG1 antibody and it is used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, and severe or disabling plaque psoriasis.
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| A008 | Denosumab Featured |
Denosumab is a human IgG2 monoclonal antibody with affinity and specificity for human RANKL (receptor activator of nuclear factor kappa-B ligand).
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| A007 | Daratumumab Featured |
Daratumumab is a human monoclonal antibody targeting CD38, an antigen uniformly expressed by plasma cells in multiple myeloma and light-chain amyloidosis (AL).
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| A006 | Cetuximab Featured |
Cetuximab, a novel molecular-targeted agent,is an inhibitor of EGFR monoclonal humanized antibody interacting with the extracellular binding site of EGFR to block ligand stimulation.
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| A005 | Bevacizumab Featured |
Bevacizumab (anti-VEGF) is a humanized anti-VEGF monoclonal antibody which binds to and neutralizes all human VEGF-A isoforms and bioactive proteolytic fragments.
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| A004 | Atezolizumab Featured |
Atezolizumab (anti-PD-L1) is a fully humanized, IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1, but not the interaction of PD-L2 with PD-1.
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| A001 | Adalimumab Featured |
Adalimumab (anti-TNF-alpha) is the first fully human, recombinant IgG1 monoclonal antibody that specifically targets human TNF-alpha.
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| DC60586 | BIO-7488 Featured |
BIO-7488 is a potent, selective, oral active and CNS-penetrant IRAK4 inhibitor with the IC50 of 0.6 nM and > 30 μM for IRAK4 and hERG, respectively.
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| DC67089 | GIBBERELLIN A51 Featured |
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| DC67088 | Gibberellin 44 Featured |
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| DC67087 | 2β,3β,4aα-Trihydroxy-1β-methyl-8-methylenegibbane-1α,10β-dicarboxylic acid 1,4a-lactone Featured |
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| DC67086 | GIBBERELLIN A20 Featured |
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| DC67085 | Gibberellin A19 Featured |
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| DC67084 | gibberellin A12 aldehyde Featured |
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| DC60689 | Gibberellin A5 Featured |
Gibberellin A5 is a plant hormone that promotes floral development.
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| DC60690 | Gibberellin A4 Featured |
Gibberellin A4 is a natural compound that can be isolated from Sphaceloma manihoticola. Gibberellin A4 is a causal agent of cassava superelongation disease.
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| DC60688 | Gibberellin A3 methyl ester Featured |
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| DC48758 | Gibberellin A1 Featured |
Gibberellin A1 is a kind of plant hormones. Gibberellin A1 is a growth-promoting acids isolated from immature seed of Phaseolus multiflorus.
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| DC49096 | (22S,23S)-Homobrassinolide Featured |
(22S,23S)-Homobrassinolide is one of the most active brassinosteroids in inducing plant growth in various plant bioassay systems. (22S,23S)-Homobrassinolide shows Akt-dependent anabolic activity in rat skeletal muscle cells. Orally active.
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| DC29108 | Pam3CSK4 TFA Featured |
Pam3CSK4 TFA is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2.
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