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Cat. No. Product Name Field of Application Chemical Structure
DC67592 Pitstop 2-100 Featured
DC67591 4-(2-(5-(3,5-dimethylisoxazol-4-yl)-2-(3-fluoro-4-(prop-2-yn-1-yloxy)phenethyl)-1H-benzo[d]imidazol-1-yl)ethyl)morpholine Featured
DC67589 Desethylatrazine-d7 Featured
Desethylatrazine-d7 is the deuterium labeled Desethylatrazine.
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DC67588 7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 6-(4-methoxyphenyl)-N-[(1R)-1-phenylethyl]- Featured
DC67587 3-chloro-N-[[(3-chloro-5-fluorophenyl)amino]thioxomethyl]benzamide Featured
DC73393 alpha-NETA Featured
alpha-NETA (α-NETA) is a small molecule antagonist of chemerin receptor chemokine-like receptor 1 (CMKLR1), inhibits chemerin-stimulated β-arrestin2 association with CMKLR1 with IC50 of 4.9 uM.
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DC60631 T-10418 Featured
T-10418 is a potent and selective G2A agonist with EC50 of 0.82 μM. T-10418 exhibits higher potency than the reference and natural ligand 9-HODE and high selectivity among G protein-coupled receptors. T-10418 is a suitable candidate for in vivo studies on therapeutic potential of G2A agonism.
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DC26092 PF-04455242 hydrochloride Featured
PF-04455242 is a potent, selective κ-opioid receptor (KOR) antagonist with Ki of 3 nM/21 nM/22 nM for hKOR/rKOR/mKOR, respectively.
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DC23423 PF-04455242 Featured
PF-04455242 is a potent, selective κ-opioid receptor (KOR) antagonist with Ki of 3 nM/21 nM/22 nM for hKOR/rKOR/mKOR, respectively.
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DC40974 GSK717 Featured
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretion in HEK293/hNOD2 cells.
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DC11594 HDAC8-IN-20a Featured
HDAC8-IN-20a is a potent, selective HDAC8 inhibitor with IC50 of 27 nM.
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DC34406 T62 Featured
T62 is an allosteric enhancer of A1 adenosine receptor.
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DC21398 AI-2 Featured
Nrf2 acticatior AI-2 is a small-molecule inducer of the antioxidant response element (ARE) that activates and stabilizes Nrf2 by covalently modifying Keap1.
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DC47307 Defibrotide sodium Featured
Defibrotide sodium is a complex mixture of single stranded polydeoxyribonucleotides. Defibrotide sodium has liver protection, anti-inflammatory, antithrombotic, profibrinolytic, and anti-ischemic properties. Defibrotide sodium can be used for sinusoidal obstruction syndrome (SOS)/veno-occlusive disease (VOD) research.
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DC26208 Remdesivir metabolite(GS-441524) Featured
Remdesivir metabolite.Remdesivir blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 Nm,and also showed potent activity blocking 2019-nCov(Coronavirus).
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DC73788 K161 Featured
K161 is a potent, pan-SHIP1/2 inhibitor with IC50 of 1.5- 6 uM and 6.5-13 uM, respectively.
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DC60852 PVTX-405 Featured
PVTX-405 is a potent, effective, highly selective, and orally efficacious IKZF2 molecular glue degrader with DC50 of  0.7 nM. PVTX-405 in combination with anti-PD1 or anti-LAG3 significantly increases animal survival compared to anti-PD1 or anti-LAG3 alone.
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DC73944 CK147 Featured
CK147 (CK-147) is a potent CD4 down-modulator with IC50 of 63 nM, inhibits Sec61-dependent cotranslational translocation of huCD4 in vitro.
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DC39823 Diphenylterazine (DTZ) Featured
Diphenylterazine (DTZ) is a bioluminescence agent. Diphenylterazine alone yielded very little background, leading to excellent signal-to-background ratios.
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DC10610 CycLuc1(Luciferase substrate) Featured
CycLuc1 is a luciferase substrate which offers brighter bioluminescence and improved imaging in mouse models at lower doses than the standard D-luciferin.
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DC65436 AkaLumine hydrochloride Featured
AkaLumine hydrochloride is a luciferin analogue, with a Km of 2.06 μM for recombinant Fluc protein.
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DC34025 AkaLumine Featured
AkaLumine is a luciferin analogue. The bioluminescence produced by AkaLumine in reactions with native firefly luciferase is in the near-infrared wavelength ranges (λmax=677?nm), and yields significantly increased target-detection sensitivity from deep tissues with maximal signals attained at very low concentrations, as compared with D-luciferin and emerging synthetic luciferin CycLuc1.
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DC45080 Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride (factor Xa specific chromogenic substrate) Featured
Suc-Ile-Glu(γ-pip)-Gly-Arg-pNA hydrochloride is a factor Xa specific chromogenic substrate.
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DC26055 Caspase-1/4 Chromogenic Substrate(Suc-YVAD-pNA) Featured
Suc-YVAD-pNA is a colorimetric substrate for caspase-1/interleukin-1β-converting enzyme (ICE) and caspase-4.
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DC11334 Suc-Ala-Ala-Pro-Abu-pNA trifluoroacetate salt Featured
Suc-AAP-Abu-pNA is a chromogenic peptide substrate for pancreatic elastase.It is cleaved by elastase to release p-nitroalinide (p-NA), which can be quantified by colorimetric detection at 405 nm as a measure of enzyme activity.
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DC40321 H-D-Phe-Pip-Arg-pNA dihydrochloride Featured
H-D-Phe-Pip-Arg-pNA (S-2238) dihydrochloride, a chromogenic substrate, is patterned after the N-terminal portion of the A alpha chain of fibrinogen, which is the natural substrate of thrombin. H-D-Phe-Pip-Arg-pNA dihydrochloride is specific for thrombin and is used to measure antithrombin-heparin cofactor (AT-III). The AT-III assay using H-D-Phe-Pip-Arg-pNA dihydrochloride is sensitive, accurate, and easy to perform.
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DC26060 H-Gly-Arg-PNA.HCl (colorimetric substrate for thrombin) Featured
H-Gly-Arg-pNA is a colorimetric substrate for thrombin.
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DC67318 S2366 HCl(chromogenic substrate for Factor XI ) Featured
S2366 HCl is a chromogenic substrate for Factor XI in plasma.
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DC53058 CH3OCO-D-CHA-Gly-Arg-pNA (Chromogenic Substrate Pefachrome FXa) Featured
CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa.
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DC11356 Ac-LEHD-pNA(Caspase-9 substrate) Featured
Ac-LEHD-pNA is a biological active peptide. (Caspase-9 substrate; pNA (4-nitroaniline)-derived caspase substrates are widely used for the colorimetric detection of various caspase activities. Cleavage of pNA peptides by caspases generates pNA that is monitored colorimetrically at ~405 nm. pNA has maximum absorption around 408 nm.)
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