Novel 11β-HSD1 inhibitor

Natural inhibitor of microRNA-21, reducing growth of cancer cells

Potent inducer of anemia

Direct-acting vasodilator with anti-tachycardiac effect

Potent and selective agonist of μ-opioid receptor (MOR) with relatively low affinity for the δ-opioid receptor and the κ-opioid receptor

Negative control for BTZO-1

Novel effective reversible and noncovalent inhibitor of DprE1.

Novel unique Na V modulator, acting as a conspicuous outlier, eliminating fast but not slow inactivation

Novel inhibitor of alpha2beta1 integrin, decreasing average platelet adhesion in individuals with the C/T807T genotype but not in those harboring C807C

The first small-molecule inhibitor with significant selectivity among the KCa2 channel subtypes

Novel potent inhibitor of Bruton’s tyrosine kinase (BTK)

Novel potent and selective covalent inhibitor of Bruton’s tyrosine kinase (BTK), targeting a noncatalytic cysteine residue (Cys481) for covalent bond formation

Novel selective and potent competitive inverse agonist of human GPR43

Novel activator of BtGH84, the first experimentally discovered small molecule activator of a glycoside hydrolase

Novel activator of PC1/3 and inhibitor of PC2

Novel cell-permeable modulator of cellular morphogenesis in yeast and mammalian cells

Novel cell-permeable modulator of cellular morphogenesis in yeast and mammalian cells; Inhibitor of SARS-CoV Mpro activity via intensive H-bond network and hydrophobic interactions

Novel respiratory syncytial virus (RSV) fusion inhibitor

Novel potent inhibitor of both HIV-1 and HIV-2 replication, being also active against the erythrocytic stages of P. falciparum

Novel potent covalent inhibitor of gut bacterial bile salt hydrolases (BSH)

Fluorescent probe visualizing neurofibrillary tangles in Alzheimer's disease

Fluorescent probe, binding to neurofibrillary tangles with high contrast and selectivity over amyloid

Fluorescent probe in vitro and in vivo aiming at a tau-based diagnosis of Alzheimer's disease

Novel proteasome inhibitor, protecting against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis

Protein kinase C (PKC) activator

Novel Ca V channels blocker, binding in the central cavity of the pore on the intracellular side of the selectivity filter, physically blocking the ion-conducting pathway

Novel PTP1B inhibitor

Antitumor agent

Mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus.

Inhibitor of the reuptake of both dopamine and serotonin in the brain