Novel potent and selective dual FLT3/AURKA inhibitor

The first potent inhibitor of Burkholderia pseudomallei methionine aminopeptidase

Squalene synthase (SQS) inhibitor, potently inhibiting CrtM

Novel CrtM inhibitor

Novel potent SQS inhibitor

Novel modulator of TTD-PHD histone reader module, binding to the TTD groove, competing with linker binding and promoting open TTD-PHD conformations

Histamine H3 receptor agonist prodrug

Novel, Potential Dengue Virus NS2B/NS3 Protease Inhibitor

Potent and selective STAT5 inhibitor

Novel and highly potent histamine H3 receptor ligand

Novel IKK-2 inhibitor, targeting the Ser177 and/or Ser181 residues in the kinase's activation loop domain.

Proteolysis targeting chimeras (PROTAC), acting as a degrader of oncogenic BCR-ABL

Novel. highly potent, selective, cell-permeable furin inhibitor, rescuing key features of cystic fibrosis airway disease

Novel BOP-conjufated fluorescent dual α9β1/α4β1 integrin inhibitor

Novel potent inhibitor of Botulinum neurotoxin/A light chain (BoNT/A LC)

Potent Botulinum Neurotoxin A Light-Chain Inhibitor

Natural inhibitor of protein tyrosine phosphatase 1B (PTP1B)

Novel fluorogenic dye for Live-Cell Fluorescence Microscopy

Fluorogenic dye for Live-Cell Fluorescence Microscopy

Novel Fluorescent, Highly Affine Histamine H3 Receptor Ligand

Novel covalent substrate-competitive inactivator of AKT kinase

Inhibitor of topoisomerase I/II, inducing DNA cross-linking and significantly suppressing the growth of various NSCLC cell lines with or without mutations in epidermal growth factor receptor (EGFR)

Selective delta 1 opioid receptor antagonist

Solvatochromic Nile Red Probe with FRET Quencher Reveal Lipid Order Heterogeneity in Living and Apoptotic Cells

Novel CD4 mimic, inhibiting HIV-1 entry into target cells with both significantly higher potency and neutralization breadth than previous congeners, while maintaining high selectivity for the target virus

Potent long-acting H2-receptor antagonist

Novel fluorescent activity-based probe (ABP), being intrinsically dark and only emitting fluorescence after reaction with the target protease, are ideally suited for imaging techniques such as small animal noninvasive fluorescence imaging and live cell fl

G-quadruplex ligand, decreasing oncogene expression

Novel pan-genotype inhibitor of HCV NS5B polymerase via binding to the primer grip site

Novel γ-secretase modulator