Similar to PROTACs in their ability to induce ternary complexes, PhosTAC7 focuses on recruiting a Ser/Thr phosphatase to a phosphosubstrate to mediate its dephosphorylation.

DBCO-N-bis(PEG4-NHS ester) is a PEG linker which contains two PEG4-NHS ester and a DBCO group. DBCO-N-bis(PEG4-NHS ester) is useful for protein modification or labeling.

ZXH-4-130 TFA is a highly potent and selective degrader of CRBN. ZXH-4-130 is a CRBN-VHL compound (hetero-PROTAC).

C18-PEG13-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

PROTAC ER Degrader-10 is a potent PROTAC ER degrader and can be used for cancer research. PROTAC ER Degrader-10 is extracted from patent WO2021133886, example 36.

PROTAC BRD9 Degrader-4 is a BRD9 bifunctional degrader for treating cancer.

PROTAC BRD9 Degrader-3 is a BRD9 bifunctional degrader for treating cancer.

SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC50s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter.

Mal-amido-PEG15-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HDAC6 degrader-1 is a PROTAC that comprises a selective HDAC6 inhibitor Nexturastat A (Nex A) as the HDAC6 binder, a linker and a ligand for recruiting E3 ligase. HDAC6 degrader-1 induces significant degradation of HDAC6, exhibits excellent selectivity against other HDACs, and demonstrates efficient inhibition of cell proliferation.

ML 2-14 is a PROTAC linker, which belongs to a polyethylene glycol (PEG) linker. ML 2-14 can be used in the synthesis of the PROTAC.

PROTAC BRD9 Degrader-2 is a BRD9 bifunctional degrader for treating cancer.

Pomalidomide-C5-Dovitinib (compound 2) is a PROTAC containing Pomalidomide, Dovitinib and connected with CRBN. Pomalidomide-C5-Dovitinib shows enhanced antiproliferative effects against FLT3-ITD+ AML cells. Pomalidomide-C5-Dovitinib induces the degradation of the FLT3-ITD and KIT proteins in a ubiquitin-proteasome-dependent manner and completely blocks their downstream signaling pathway. Pomalidomide-C5-Dovitinib has the potential for the research of FLT3-ITD+ acute myeloid leukemia.

m-PEG18-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-N-amido-PEG15-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG10-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

HO-PEG18-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG14-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

N-bis(t-boc-N-amido-PEG3)-N-(PEG3-acid) hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

m-PEG15-acetic acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG12-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG10-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG9-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-Aminooxy-PEG11-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Biotin-PEG6-NH-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG10-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-N-amido-PEG10-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

t-Boc-amido-PEG10-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Dodecylheptaglycol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Acid-PEG9-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.