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Eptifibatide

  Cat. No.:  DC37766   Featured
Chemical Structure
188627-80-7
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More than 5000 active chemicals with high quality for research!
Field of application
Eptifibatide is a potent glycoprotein IIb/IIIa antagonist (GPIIb/IIIa; Kd = 120 nM) that inhibits platelet aggregation. Eptifibatide prevents binding of the adhesion proteins fibrinogen and von Willebrand factor to GPIIb/IIIa on the surface of activated platelets to prevent aggregation and thrombus formation. It inhibits ADP-induced citrated blood aggregation (IC50 = 0.11-0.22 μg/ml) in vitro and in vivo (IC50 = 52 μg/ml in porcine plasma). Formulations containing eptifibatide have been used to reduce risk of thrombolysis in myocardial infarction in patients undergoing percutaneous coronary intervention.
Chemicals PropertiesBiological activity Related products COA MSDS Datasheet
Cas No.: 188627-80-7
Chemical Name: Eptifibatide
Synonyms: Eptifibatide;MAP-LYS-GLY-ASP-TRP-PRO-CYS-NH2;INTEGRELIN;N6-(Aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide;{MPA}{HAR}GDWPC-NH2;MPA-HAR-Gly-Asp-Trp-Pro-Cys-NH2;MPA-HAR-GLY-ASP-TRP-PRO-CYS-NH2(DISULFIDE BRIDGE, MPA1-CYS6);Intrifiban;3-Mercaptopropionyl-HoMoarg-Gly-Asp-Trp-Pro-Cys-NH2;N6-(AMinoiMinoMethyl)-N2-(3-Mercapto-1-oxopropyl)-L-lysylglycyl-L-.alpha.-aspartyl-L-tryptophyl-L-prolyl-L-cysteinaMide Cyclic (16)-Disulfide;Eptifibatide impurity;Integrilin;Eptifibatide Acetate;C35H49N11O9S2;NA8320J834;DSSTox_RID_81810;DSSTox_CID_26673;DSSTox_GSID_46673;S(1),S(6)-cyclo[N(6)-carbamimidoyl-N(2)-(3-sulfanylpropanoyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide];N(6)-amidino-N(2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide;[(3R,11;AKOS015895205;NCGC00167505-01;EPTIFIBATIDE [INN];NCGC00263524-01;Eptifibatide Accord (generic);[(3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl]acetic acid;EX-A3111;GTPL6585;Tox21_112503_1;EPTIFIBATIDE (MART.);N(sup 6)-Amidino-N(sup 2)-(3-mercaptopropionyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide, cyclic(1-6)-disulfide;L-Cysteinamide,N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-;CHEMBL1174;Sch-60936;7H-Pyrrolo(2,1-g)(1,2,5,8,11,14,17,20)dithiahexaazacyclotricosine-17-acetic acid, 3-(aminocarbonyl)-11-(4-((aminoiminomethyl)amino)butyl)docosahydro-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxo-, (3R,11S,17S,20S,25aS)-;CHEBI:291902;eptifibatidum;C73610;BDBM50092098;L-Cysteinamide, N6-(aminoiminomethyl)-N2-(3-mercapto-1-oxopropyl)-L-lysylglycyl-L-alpha-aspartyl-L-tryptophy-L-prolyl-, cyclic (1-6)-disulfide;Eptifibatide [INN:BAN];HY-B0686;EPTIFIBATIDE [ORANGE BOOK];NCGC00167505-03;Tox21_112503;188627-80-7;DTXCID5026673;C68-22;A-aspartyl-L-tryptophyl-L-prolyl-, cyclic (1 inverted exclamation marku6)-disulfide;EPTIFIBATIDE [EMA EPAR];epifibratide;((3R,11S,17S,20S,25aS)-11-(4-carbamimidamidobutyl)-3-carbamoyl-20-(1H-indol-3-ylmethyl)-1,9,12,15,18,21-hexaoxodocosahydro-7H-pyrrolo(2,1-g)(1,2,5,8,11,14,17,20)dithiahexaazacyclotricosin-17-yl)acetic acid;CCG-270517;Q2295855;EPTIFIBATIDE [MI];SCHEMBL15781;Eptifibatide acetate?;AKOS025147403;EPTIFIBATIDE [USAN];EPTIFIBATIDE [VANDF];157630-07-4;1-[(1R)-1-Phenylethyl]-1Himidazole-5-carboxylic acid ethyl ester; (+)-Ethyl 1-(;HSDB 8313;UNII-NA8320J834;CZKPOZZJODAYPZ-LROMGURASA-N;2-[(3S,6S,12S,20R,23S)-20-carbamoyl-12-[4-(diaminomethylideneamino)butyl]-3-(1H-indol-3-ylmethyl)-2,5,8,11,14,22-hexaoxo-17,18-dithia-1,4,7,10,13,21-hexazabicyclo[21.3.0]hexacosan-6-yl]acetic acid;EPTIFIBATIDE [MART.];[22-Carbamoyl-14-(4-guanidino-butyl)-5-(1H...
SMILES: S1C([H])([H])[C@@]([H])(C(N([H])[H])=O)N([H])C([C@]2([H])C([H])([H])C([H])([H])C([H])([H])N2C([C@]([H])(C([H])([H])C2=C([H])N([H])C3=C([H])C([H])=C([H])C([H])=C23)N([H])C([C@]([H])(C([H])([H])C(=O)O[H])N([H])C(C([H])([H])N([H])C([C@]([H])(C([H])([H])C([H])([H])C([H])([H])C([H])([H])/N=C(\N([H])[H])/N([H])[H])N([H])C(C([H])([H])C([H])([H])S1)=O)=O)=O)=O)=O)=O
Formula: C35H49N11O9S2
M.Wt: 831.9619
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
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