Novel potent and selective peripheral AAK1 inhibitor

Potent antimitotic and oral tubulin binding agent, significantly inhibiting growth of a human non-small-cell lung tumor

Potent ligand of the 5-HT7 receptor

Novel LOX-activity sensor for cross-linking with a collagen peptide to chemoselectively target endogenous aldehydes generated by LOX

Lopinavir Secondary Metabolite

Opioid receptor agonist, acting on the µ-opioid receptors in the myenteric plexus of the large intestine

Natural neurotrophic agent

Antibiotic for treatment of bacterial infections including bronchitis and urinary tract infections, prevent urinary tract infections prior to surgery

Inhibitor of the Vesicular_monoamine_transporter_2>vesicular monoamine transporter-2 (VMAT2)

Novel potent and specific agonist of I 1 imidazoline receptors

Potent and selective ligand of imidazoline 1 receptor (I 1 R)

Novel Two-in-One Mutant-Selective Epidermal Growth Factor Receptor Inhibitor That Spans the Orthosteric and Allosteric Sites

Novel highly selective inhibitor of the low-molecular-weight protein tyrosine phosphatase (LMPTP), being highly orally bioavailable and reversing obesity-induced diabetes in mice

Novel AI-2 quorum-sensing inhibitor, affecting the starvation response and reducing virulence in several Vibrio species, most likely by interfering with LuxPQ

Novel p75NTR antagonist

Novel Probe for Imaging Tau Pathology in Transgenic Mouse and Rat Models

Negative control for LM11A-24

Novel Modulator of p75NTR-dependent motor neuron death

Novel inhibitor of kallikrein-related peptidase 7 (KLK7) and epidermal elastase 2 (ELA2)

Novel inducer of biofilm dispersal, having a slower rate of NO release

Highly

Potent, selective, and orally active inhibitor of semicarbazide-sensitive amine oxidase (SSAO) activity, inhibiting vascular adhesion protein 1 (VAP-1) activity and decreasing the density of macrophages in inflamed atherosclerotic plaques in mice

Novel pan-inhibitor of sialyltransferase (ST)

The first fluorogenic dipeptide probe for

The first inhibitor of the catalytic activity of AChE and AChE-induced amyloid-beta aggregation protecting against reactive oxygen species

Lipid II binder, causing specific upregulation of the vancomycin-resistance associated gene vraX which is implicated in the cell wall stress stimulon that confers glycopeptide resistance

5HT-4 antagonist with moderate 5HT-3 antagonist properties

Novel Fused Benzodiazepine Hybrid Payload for Antibody-Drug Conjugate (ADC)

Natural capsid inhibitor

Novel inhibitor of the oncogenic Lin28-let-7 interaction