Inhibitor of human tyrosyl-DNA phosphodiesterase 1 (TDP1); Delayed death inhibitor of the malarial parasite plastid; Inhibitor of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1); Inhibit

Inhibitor of PLAP and TNAP

Novel specific inhibitor of bacterial AddAB helicase-nuclease DNA repair enzyme

Potent inhibitor of cancer cell growth with microtubule-binding activity

Potent inhibitor of HIV-1 nucleocapsid (NC)-DNA interaction; specifically bound NC with nanomolar affinity, and showed modest anti-HIV-1 activity in ex vivo cell assays

Novel Stimulator of Hepatitis C Virus NS3 Helicase-Catalyzed ATP Hydrolysis

Potent inhibitor of ROCK2 enzymatic activity

Potent inhibitor of cancer cell growth with microtubule-binding activity

Novel Inhibitor of the Major Facilitator Superfamily (MFS) of Efflux Pump Transporters.

Novel lopinavir analogue against COVID-19, forming the most stable complex with the Mpro

Novel inhibitor of Cdc42 that act by blocking nucleotide binding with no effect on RhoA or Rac

Blocker of integrin binding to its endothelial receptor (VCAM-1)

Antibacterial agent, being effective in treating dapsone resistant leprosy

Novel Selective Agonist of GPR55

Novel inhibitor against the NS3/4A serine protease of Hepatitis C virus genotype 3

Novel specific anti-VEEV (Anti-Venezuelan Equine Encephalitis Virus) agent

HIV-1 Rev pre-integration inhibitor

Novel Selective Agonist of GPR55

Novel Selective Agonist of GPR55

Stimulator of nitric oxide release and scavenger of superoxide

Novel SOCE modulator, displaying selectivity over other calcium channels, such as TRPV1, TRPM8, and voltage-operated calcium channels

Novel inhibitor of E3 ligase activity of cIAP1, antagonizing c-MYC by stabilizing MAD1 protein in cells

Novel chymase inhibitor, exhibiting concentration-dependent chymase inhibitory activity

Novel Non-peptide GLP-1R Agonist, adopting a unique binding mode with a more open receptor conformation at the extracellular face

Novel inhibitor of superoxide anion (O2(-)) generation; Inhibitor of phospholipase D activation; Modulator of immune cell migration via RhoA activity inhibition; Inhibitor of Rac2 activation in stimulated neutrophils

Novel inhibitor of 6-hydroxydopamine induced apoptosis in SH-SY5Y cells via mitochondria protection and NF-κB modulation

Novel potent BMP potentiator with osteogenic efficacy, enhancing canonical BMP outputs at the expense of TGFβ-Smads in an unprecedented manner

Potent and selective partial agonist of ecdysone receptor (EcR)

Natural phytosterol, showing antidiabetes activities

Antioxidant; Aldose reductase inhibitor