Novel selective ligand of the Transport Inhibitor Resistant 1 (TIR1)

Membrane-permeant activator of cAMP-dependent protein kinase (PKA), selectively for site A-I of PKA

Novel inhibitor of STAT3 activation, suppressing proliferation, inducing cell cycle arrest and apoptosis in breast cancer

ATP analog for specific interaction with modified receptor proteins in chemical genetics approach

Precursor for radio-labelled triphosphate to be used in chemical genetics approach

Natural blocker of Kv1.2 channels, not involving direct occlusion of the outer pore but depending on C-type inactivation

Broad-spectrum metabolic inhibitor, inhibiting glucose uptake, decreasing glycolysis and ATP with minimal changes in ROS and mitochondrial respiration

Widely used fucosylation probe, strongly inhibiting fucosylation and GDP-fucose synthetase FX, halting hepatoma invasion

Novel fluorescent probe for near-IR live-cell super-resolution imaging

Novel methuselah (Mth)-specific antagonist

Antioxidant, inhibiting Cu(2+)-mediated oxidation of human low density lipoprotein (LDL)

Novel potent MtbCoaBC inhibitor (IC50: 0.08 µM)

Metabolite of soy isoflavones

Metabolite of soy isoflavones

Metabolite of soy isoflavone; Antioxidant

Novel FUdR prodrug. possessing a better tumor inhibition rate and a better metabolic stability than FUdR through a ATB0, -mediated prodrug approach

Novel O-GlcNAc transferase (OGT) inhibitor, inducing dose- and time-dependent decreases in O-GlcNAc levels

Blocker of the formation of the FAK/Mdm-2 complex; subsequently, activating p53 and caspase-8 and leading to increase detachment and apoptosis in breast and colon cancers

Natural inhibitor of hedgehog (Hh) signal transduction, diminishing characteristics of cancer stem cells, leading to decreasing production of the Hh target proteins BCL2, PTCH1, and BMI1

PhIP metabolite

Inducer of neurite outgrowth via cAMP/PKA/CREB pathway in PC12 cells

Novel highly potent nonsteroidal antiandrogen (NSAA)

Neutral allosteric site ligand of the metabotropic glutamate receptor subtype 5 (mGlu5), blocking the effects of both the allosteric antagonist MPEP and potentiator CDPPB

Novel potent δ-selective allosteric modulator, displayed at least 60-fold selectivity for α4β1δ over α4β1γ2 receptor subtypes, Ki(α4β1δ

Natural proangiogenic agent, downregulating the cellular uptake of all- trans-retinoic acid (atRA) under hypoxia

Melatonin analogue, selectively binding on MT3 subsites

Active metabolite of diclofenac, targeting COX and CaMKIIα hub domain

Morin isomer, antioxidant

Metabolite of dantrolene

Novel potent and selective G protein-biased 5-HT 7 R Antagonist, significantly reducing self-grooming duration time to the level of wild-type mice