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| Cas No.: | 432037-57-5 |
| Chemical Name: | [4-[[N'-[6-(4-chlorophenoxy)hexyl]-N-cyanocarbamimidoyl]amino]pyridin-1-ium-1-yl]methyl 2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethyl carbonate chloride |
| Synonyms: | GMX1777 chloride;Teglarinad;EB-1627 |
| SMILES: | C(OC[N+]1C=CC(N/C(=N\CCCCCCOC2=CC=C(Cl)C=C2)/NC#N)=CC=1)(=O)OCCOCCOCCOCCOC.[Cl-] |
| Formula: | C30H43Cl2N5O8 |
| M.Wt: | 672.601 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | The water-soluble prodrug of GMX-1778 (CHS-828), which is a potent and specific inhibitor of the NAD(+) biosynthesis enzyme NAMPT with IC50 of <20 nM; shows anticancer activity in clinical trials, can be used in combination with other drugs to treat malignant melanoma. |