IDO-IN-6|CAS 1402837-76-6|DC Chemicals

Cas No.:	1402837-76-6
Chemical Name:	IDO-IN-6
SMILES:	O[C@H](CC1)CC[C@]1([H])[C@@H](O)C[C@@H]2N3C(C4=C2C(F)=CC=C4)=CN=C3
Formula:	C₁₈H₂₁FN₂O₂
M.Wt:	316.37
Sotrage:	Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month

Cat. No.	Product name	Field of application
DC47597	IDO-IN-14	IDO-IN-14 is an IDO inhibitor with an IC50 value of 0.6928 nM.
DC47596	IDO-IN-15	IDO-IN-15 is an IDO1 inhibitor (IC50 < 0.51 nM).
DC46155	BMT-297376	BMT-297376, the optimized Linrodostat, is a potent IDO1 inhibitor.
DC42338	IDO-IN-8	IDO-IN-8 (NLG-1487) is an indoleamine 2,3-dioxygenase (IDO) extracted from patent WO WO2012142237A1, compound 1487, has an IC50 of 1-10 μM.
DC42337	IDO-IN-6	IDO-IN-6 (NLG-1486) is an indoleamine 2,3-dioxygenase (IDO) extracted from patent WO WO2012142237A1, Compound 1486, has an IC50 of <1 μM.
DC40744	(Rac)-Indoximod	(Rac)-Indoximod (1-Methyl-DL-tryptophan) is an indoleamine 2,3-dioxygenase (IDO) inhibitor. Co-treatment with IFN-γ and (Rac)-Indoximod markedly reduces the activity of human cardiac myofibroblasts (hCMs) expressing α-SMA and induces apoptosis through up-regulating the IRF-1, Fas, and FasL genes.
DC28673	IDO1-IN-2	IDO1-IN-2 (compound 16) is a potent and selective IDO1 inhibitor with IC50s of 81 nM, 59 nM (mouse) and 28 nM (rat), respectively. IDO1-IN-2 has anti-cancer activity.
DC28284	(S)-IDO1-IN-5	(S)-IDO1-IN-5 (Example 1B) is an active S-isomer of IDO1-IN-5. (S)-IDO1-IN-5 binds to IDOL with an IC50 value less than 1.5 µΜ. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
DC28283	(Rac)-IDO1-IN-5	(Rac)-IDO1-IN-5 (Example 1) is a racemate of IDO1-IN-5. IDO1-IN-5 is a potent, selective and brain penetrated inhibitor of Indoleamine 2,3-Dioxygenase 1 (IDO1) activity, binds to apo-IDO1 lacking heme rather than mature heme-bound IDO1.
DC11159	Roxyl-WL	Roxyl-WL is a highly potent and selective inhibitor of IDO1 with IC50 of 1 nM.