FGIN-1-27|CAS 142720-24-9|DC Chemicals

Cas No.:	142720-24-9
Chemical Name:	1H-Indole-3-acetamide,2-(4-fluorophenyl)-N,N-dihexyl-
Synonyms:	1H-Indole-3-acetamide,2-(4-fluorophenyl)-N,N-dihexyl-;2-[2-(4-fluorophenyl)-1H-indol-3-yl]-N,N-dihexylacetamide;FGIN-1-27;Fgin 1 27;Lopac-D-8555;N,N-Dihexyl-2-(4-fluorophenyl)indole-3-acetamide;Tocris-0658
SMILES:	FC1C=CC(C2=C(CC(N(CCCCCC)CCCCCC)=O)C3C(=CC=CC=3)N2)=CC=1
Formula:	C₂₈H₃₇N₂OF
M.Wt:	436.60458
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Cat. No.	Product name	Field of application
DC70409	FGIN-1-27	FGIN-1-27 is an anxiolytic compound that acts as a selective agonist at the peripheral benzodiazepine receptor (TSPO).FGIN-1-27 inhibited Th17 cell differentiation, significantly downregulated the expression of RORγt target genes, notably Il17a, Il17f, Il23r, Ltb4r1,Ccr6.FGIN-1-27 protected mice against EAE, induced amino acid starvation response (AAR), FGIN-1-27 produced anti-anxiety and anti-panic effects in non-mammalian models.
DC11640	PK-11195	PK 11195 is a ligand of translocator protein. It targets Leishmania chemotherapy (IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively).
DC11650	Ro5-4864	A potent, selective ligand for the mitochondrial translocator protein 18kDa (TSPO/PBR).