Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3.

TP808 is a useful intermediate for the synthesis of diverse tetracycline antibiotics.

TPPU is a potent inhibitor of both human and mouse sEH (IC50 = 3.7 and 2.8 nM, respectively).

TPT-260 2Hcl (TPU260 2Hcl) is a thiophene thiourea derivative with molecule weight 260.00 in free base form; There is no formal name yet, we temporally call this molecule as TPT-260.

TR-14035 is a a dual alpha4beta7(IC50=7 nM)/alpha4beta1 (IC50=87 nM) integrin antagonist .

Transcrocetin (trans-Crocetin), extracted from saffron (Crocus sativus L.), acts as an NMDA receptor antagonist with high affinity.

CM 10 is an ALDH1A inhibitor that depletes CD133+ cancer stem cells.

TRC051384 is a heat shock protein 70 (HSP70) inducer.

Treprostinil sodium is a potent DP1 and EP2 agonist with EC50 values of 0.6±0.1 and 6.2±1.2 nM, respectively.

TRi-1 (TXNRD1 inhibitor 1) is a potent, specific and irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1) with anticancer potential, 5- to 10-fold higher specificity for TXNRD1 over TXNRD2.

Trifluridine (Viroptic)

Trilostane(Win 24540; Modrastane) is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.

TrkA inhibitor compound 23 is an allosteric, potent, Subtype Selective and Peripherally Restricted TrkA Kinase Inhibitor， with IC50 of 10 nM, 180-fold selective over TrkB and 70-fold selective over TrkC in cell based assays.

Trovirdine inhibits HIV-1 RT with an IC50 of 7 nM when employing heteropolymeric primer/template (oligo-DNA/ribosomal RNA)and dGTP as substrate.

Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.

TUG-1375 (TUG1375, TUG 1375) is a potent, selective free fatty acid receptor 2 (FFA2/GPR43) agonist with β-arrestin-2 pEC50 of 6.1 and cAMP pEC50 of 7.11.

Tyroserleutide is a tripeptide consisting of tyrosine, serine, and leucine with potential antineoplastic activity.

Tyrphostin AG 528 is an inhibitor of EGFR and ErbB2 with IC50s of 4.9 and 2.1 μM, respectively.

U-0126 is a selective MAP Kinase Kinase inhibitor, displaying a preference for MEK-1 (IC50 = 72 nM) and MEK-2 (IC50 58nM).

Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.

UNC2881 is a potent and specific Mer kinase inhibitor; inhibits steady-state Mer kinase phosphorylation with an IC50 value of 22 nM.

Uprosertib is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity.

UVI 3003 is a highly selective antagonist of retinoid X receptor (RXR), and inhibits xenopus and human RXRα in Cos7 cells, with IC50s of 0.22 and 0.24 μM, respectively.

V-9302 is a competitive antagonist of transmembrane glutamine flux, selectively and potently targeting the amino acid transporter ASCT2.

Valbenazine(NBI-98854) is a potent and selective VMAT2 inhibitor..

Velaresol, also known as BW12C or BW12C79, is a oxyhaemoglobin stabilizer.

Verdiperstat is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders.

Verucerfont(GSK561679) is a corticotropin-releasing factor receptor 1 (CRF1) antagonist with IC50s of ~6.1, >1000 and >1000 nM for CRF1, CRF2, and CRF-BP, respectively.

Vilanterol trifenatate (GW642444)is a novel, inhaled, long-acting β(2) agonist with inherent 24-h activity under development as a once-daily combination therapy with an inhaled corticosteroid for COPD and asthma.

Vildagliptin (LAF-237; NVP-LAF 237) inhibits DPP-4 with IC50 of 2.3 nM.