Umibecestat|

Cas No.:	1387560-01-1
Chemical Name:	Umibecestat free base
SMILES:	C(C(NC1=NC([C@@](C)2N=C(N)[C@@](C)(C(F)(F)F)OC2)=C(F)C=C1)=O)1=NC=C(C(F)(F)F)C=C1Cl
Formula:	C₁₉H₁₅ClF₇N₅O₂
M.Wt:	513.8
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

beta-secretase inhibitor

Cat. No.	Product name	Field of application
DC9901	Verubecestat (MK-8931)	MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
DC5053	LY2886721	LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
DC5180	LY2811376	LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM.
DC11551	Elenbecestat	Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease..
DC11105	Umibecestat	beta-secretase inhibitor.
DC8400	AZD3839	AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.