Elenbecestat|E2609;E-2609

Cas No.:	1388149-39-0
Chemical Name:	N-(3-((4aS,5S,7aS)-2-amino-5-(trifluoromethyl)-4a,5-dihydro-4H-furo[3,4-d][1,3]thiazin-7a(7H)-yl)-4-fluorophenyl)-5-(difluoromethyl)pyrazine-2-carboxamide
Synonyms:	E2609;E-2609
SMILES:	C(C(NC1=CC=C(F)C([C@@]23CO[C@@H](C(F)(F)F)[C@]2([H])CSC(N)=N3)=C1)=O)1=NC=C(C(F)F)N=C1
Formula:	C₁₉H₁₅F₆N₅O₂S
M.Wt:	491.412
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease.

Cat. No.	Product name	Field of application
DC9901	Verubecestat (MK-8931)	MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
DC5053	LY2886721	LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
DC5180	LY2811376	LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM.
DC11551	Elenbecestat	Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease..
DC11105	Umibecestat	beta-secretase inhibitor.
DC8400	AZD3839	AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.