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Home > RNA Delivery > Cationic/Ionizable Lipids > Ionizable Lipids for in vivo CAR

Ionizable Lipids for in vivo CAR

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Cat. No. Product Name Field of Application Chemical Structure
DC60664 Si12-C10
Si12-C10 is a siloxane-incorporated lipid for spleen-targeting mRNA delivery. The siloxane moieties enhance cellular internalization of mRNA-LNPs and improve their endosomal escape capacity, augmenting their mRNA delivery efficacy.
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DC60575 U-101 Featured
U-101 is an ionizable lipid for mRNA delivery. U101-LNP/IL-2F mRNA formulation demonstrats effective antitumor activity and safety.LNPs containing lipid U 101 and encapsulating mRNA encoding a fusion protein composed of IL-2, a linker, and CD25 inhibit tumor growth in an MC-38 mouse xenograft model.
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