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Cat. No. Product Name Field of Application Chemical Structure
DC23923 D-Glutamic acid Featured
The one form of glutamic acid found in nature, is the most potent natural inhibitor of glutathione synthesis.
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DC24002 Adrafinil Featured
The prodrug of modafinil that is a mild central nervous system stimulant drug used to relieve excessive sleepiness and inattention..
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DC24070 ZM39923 Featured
ZM39923 is a potent, selective JAK3 inhibitor with pIC50 of 7.1, also potently inhibits human tissue transglutaminase (TGM2) with IC50 of 10 nM.
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DC20142 γ-Aminobutyric acid (4-Aminobutyric acid) Featured
γ-Aminobutyric acid (4-Aminobutyric acid) is a major inhibitory neurotransmitter in the adult mammalian brain, binding to the ionotropic GABA receptors (GABAA receptors) and metabotropic receptors (GABAB receptors).
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DC24059 PI-103 hydrochloride Featured
A potent, dual class I PI3K/mTOR inhibitor with IC50 of 2/3/3/15/ for p110α/β/δ/γ, respectively.
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DC22488 Corticotropin-releasing factor (human) Featured
Corticotropin-releasing hormone (CRH) is a peptide hormone involved in the stress response..
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DC21684 Ryuvidine Featured
Ryuvidine is a potent, selective CDK4 inhibitor with IC50 of 6.0 uM, displays >30-fold selectivity over CDK2 (IC50>100 uM).
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DC34066 Propidium Iodide Featured
Propidium Iodide is a fluorescent intercalating agent that can be used to stain cells. Propidium Iodide is used as a DNA stain in flow cytometry to evaluate cell viability or DNA content in cell cycle analysis, and in microscopy to visualise the nucleus and other DNA-containing organelles. Propidium Iodide cannot cross the membrane of live cells, making it useful to differentiate necrotic, apoptotic and healthy cells.
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DC29181 Neryl acetate Featured
Neryl acetate is a chemical compound isolated from citrus oils.
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DC29159 Nonadecanoic acid Featured
Nonadecanoic acid is a 19-carbon long saturated fatty acid. Nonadecanoic acid is the major constituent of the substance secreted by Rhinotermes marginalis to defence.
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DC28128 (S)-Trolox Featured
(S)-Trolox is a analogue of vitamin E, in which the phytyl chain is replaced with a carboxyl group. (S)-Trolox is frequently used as a model compound for studies of structural features, as well as a standard for evaluation of antioxidant activity. (S)-Trolox has potent and specific neuroprotective and antioxidant effects.
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DC24048 NVP-BKM120 hydrochloride Featured
A potent, selective, orally bioavailable inhibitor of class I PI3K isoforms with IC50 of 52 nM/166 nM/116 nM/262 nM for p110α/β/δ/γ, respectively.
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DC34751 DTSSP Crosslinker Featured
DTSSP Crosslinker, or 3,3′-Dithiobis[sulfosuccinimidylpropionate], is a homobifunctional protein crosslinker that is cell membrane impermeable. DTSSP crosslinker can be used to crosslink extracellular and membrane proteins.
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DC24068 AVL-292 besylate Featured
AVL-292 besylate (Spebrutinib, CC-292) is a highly selective, covalent Btk inhibitor with IC50 of <1 nM.
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DC24090 KX2-391 dihydrochloride Featured
A highly selective, non-ATP competitive substrate-pocket-directed Src/pretubulin inhibitor.
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DC29169 Vanillin acetate Featured
Vanillin acetate is easily synthesized from vanillin by treatment with acetic anhydride.
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DC29067 Spermidine trihydrochloride Featured
Spermidine trihydrochloride maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine trihydrochloride significantly decreases the H2O2 and O2.- contents.
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DC31650 Dicumarol Featured
Dicoumarol (INN) or dicumarol (USAN) is a naturally occurring anticoagulant that functions as a functional vitamin K depleter (similar to warfarin, a drug that dicoumarol inspired). It is also used in biochemical experiments as an inhibitor of reductases. Like all 4-hydroxycoumarin drugs it is a competitive inhibitor of vitamin K epoxide reductase, an enzyme that recycles vitamin K, thus causing depletion of active vitamin K in blood. This prevents the formation of the active form of prothrombin and several other coagulant enzymes. These compounds are not antagonists of Vitamin K directly—as they are in pharmaceutical uses—but rather promote depletion of vitamin K in bodily tissues allowing vitamin K's mechanism of action as a potent medication for dicoumarol toxicity. The mechanism of action of Vitamin K along with the toxicity of dicoumarol are measured with the prothrombin time (PT) blood test. (Source: https://en.wikipedia.org/wiki/Dicoumarol).
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DC45134 2′-O-Methyluridine Featured
2'-O-methyluridine is found in rRNA, snRNA, snoRNA and tRNA of Archaea, Bacteria, and Eukaryota.
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DC33388 Amphotericin B Featured
Amphotericin B binds ergosterol and induces membrane pore formations, increasing ROS and suppressing fungal growth. It also increases expression of IL-1-beta, TNF-alpha, BDNF and GDNF and protects against prion-induced neurodegeneration.
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DC36108 Abamectin Featured
Abamectin is a mixture of the macrocyclic lactones Avermectin B1a and Avermectin B1b. It has both insecticidal and anthelmintic actions and is used in both agriculture and veterinary medicine. Abamectin can inhibit nicotinic acetylcholine receptors of worms and can also inhibit chikungunya and yellow fever viruses. It is sometimes used for mosquito control.
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DC32057 MK-933 Featured
Ivermectin is a medication that is effective against many types of parasites. It is used to treat head lice, scabies, river blindness, strongyloidiasis, and lymphatic filariasis, among others. Ivermectin and other avermectins (insecticides most frequently used in home-use ant baits) are macrocyclic lactones derived from the bacterium Streptomyces avermitilis. Ivermectin kills by interfering with nervous system and muscle function, in particular by enhancing inhibitory neurotransmission. Ivermectin is a mixture of mostly avermectin H2B1a (CAS# 71827-03-7) with some avermectin H2B1b (CAS# 70209-81-3), which are macrolides from STREPTOMYCES avermitilis.
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DC12660 NFAT Inhibitor-1 Featured
NFAT inhibitor is a cell-permeable compound that selectively inhibits calcineurin-mediated dephosphorylation of NFAT.
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DC71953 dTAGV-1-NEG Featured
dTAGV-1-NEG is a diastereomer and as a heterobifunctional negative control of dTAGV-1. dTAGV-1 is an FKBP12F36V-selective degrader.
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DC71843 BAY 1135626 Featured
BAY 1135626 is used to synthesize BAY 1129980, and use to anti-tumor research. BAY 1129980 is a Auristatin-based anti-C4.4A (LYPD3) antibody–drug conjugate (ADC), is used to non–small cell lung cancer (NSCLC) research.
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DC45629 Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH Featured
Fmoc-L-Asn(beta-D-GlcNAc(Ac)3)-OH (Fmoc-Asn(Ac3AcNH-beta-Glc)-OH) can be used in the synthesis of silicon-fluoride acceptor (SiFA) derivatized octreotate derivatives. SiFA-octreotate analogues, as tumor imaging agents, are useful tool for the research of positron emission tomography (PET).
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DCC0857 Azide-a-dsbso Featured
Azide-A-DSBSO crosslinker is a mass spectrometry (MS)-cleavable, membrane-permeable, homobifunctional, azide-labeled, acid-cleavable cross-linked peptide. Azide-A-DSBSO crosslinker enables the study of protein-protein interactions via cross-linking mass spectrometry (XL-MS).
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DC71096 OB-24 Featured
OB-24 is a potent inhibitor of heme oxygenase-1 (HO-1). Heme oxygenase-1, a member of the heat shock protein family, plays a key role as a sensor and regulator of oxidative stress. OB-24 significantly inhibited cell proliferation in vitro and tumor growth and lymph node/lung metastases in vivo. OB-24 has potential for the research of advanced prostate cancer (PCA).
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DC32971 Glibornuride Featured
Glibornuride is a blocker of adenosine 5'-triphosphate (ATP)-sensitive K+ channels (KATP channels).
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DC36136 Immethridine (hydrobromide) Featured
Immethridine (hydrobromide) is a histamine agonist selective for the H3 subtype.
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