MDVN1003

  Cat. No.:  DC10650   Featured
Chemical Structure
2058116-52-0
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More than 5000 active chemicals with high quality for research!
Field of application
MDVN1003 is a potent inhibitor of BTK amd PI3K delta.
Cas No.: 2058116-52-0
Chemical Name: 1-(5-Amino-2,3-dihydro-1H-inden-2-yl)-3-(8-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Synonyms: MDVN1003;1-(5-amino-2,3-dihydro-1H-inden-2-yl)-3-(8-fluoro-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine;BDBM50201726
SMILES: FC1C2=C(C([H])=C(C=1[H])C1C3=C(N([H])[H])N=C([H])N=C3N(C3([H])C([H])([H])C4C([H])=C([H])C(=C([H])C=4C3([H])[H])N([H])[H])N=1)N([H])C([H])([H])C([H])([H])O2
Formula: C22H20FN7O
M.Wt: 417.4389
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: MDVN1003 is a potent inhibitor of BTK amd PI3K delta.
In Vitro: MDVN1003 is a potent inhibitor of BTK amd PI3K delta. MDVN1003 inhibits Bruton's tyrosine kinase (BTK) and phosphatidylinositol-3-kinase delta (PI3K��), two proteins regulated by the B cell receptor (BCR) that drive the growth of many NHLs. MDVN1003 induces cell death in a B cell lymphoma cell line but not in an irrelevant erythroblast cell line.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
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