PPAR

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Cat. No.	Product Name	Field of Application
DC11751	UHC1	A novel potent, non-agonist PPARγ ligand that blocks CDK5-mediated PPARγ phosphorylation, without the classical agonism.
DC11750	SR-1664 Featured	SR-1664 is a novel potent, non-agonist PPARγ ligand that blocks the Cdk5-mediated phosphorylation in vitro (IC50=80 nM) and in vivo, without the classical agonism.
DC9088	Bezafibrate	Bezafibrate(BM15075) is the first clinically tested dual and pan-PPAR co-agonism.
DC9252	BMS-687453 Featured	BMS687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) α agonist, with an EC50 of 10 nM for human PPARα and ∼410-fold selectivity vs human PPARγ in PPAR-GAL4 transactivation assays.
DC12025	CDDO imidazolide Featured	CDDO-imidazolide is a potent inducer of heme oxygenase-1 and Nrf2/ARE signaling,with potent antiproliferative, differentiating, and anti-inflammatory activities.
DC10727	Elafibranor(GFT505) Featured	Elafibranor is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively.
DC9086	Fenofibrate	Fenofibrate is PPARα agonist with EC50 of 18 μM and 30 μM for mouse and human PPARα, respectively.
DC11187	Fonadelpar	Fonadelpar (NPS-005,SJP-0035) is a potent, selective peroxisome proliferator activated receptor δ (PPARδ) agonist for the treatment of corneal disorders..
DC1036	GSK-0660 Featured	GSK-0660 is a selective PPARδ antagonist (IC50 values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ respectively).
DC1035	GSK3787 Featured	GSK3787 is as a potent and selective antagonist of PPARδ with pIC50 of 6.6.
DC2078	GW-7647 Featured	GW 7647 is a potent PPARα agonist with 200-fold selectivity over PPARγ and PPARδ.
DC9904	GW0742 Featured	GW0742 is a potent PPARβ and PPARδ agonist, with an IC50 of 1 nM for human PPARδ in binding assay, and EC50s of 1 nM, 1.1 μM and 2 μM for human PPARδ, PPARα, and PPARγ, respectively.
DC7149	GW1929 Featured	GW1929 is a synthetic peroxisome proliferator-activated receptor-γ (PPARγ) agonist with IC50 of 6.2 nM and 13 nM for human and mouse, respectively.
DC4233	GW501516 Featured	GW501516 is the most selective and potent PPARβ (EC50=1.1nM) agonist that has been demonstrated to be 1,000-fold more selective in comparison to existing subtypes.
DC2079	GW-9662 Featured	GW9662 is a selective PPAR antagonist, inhibiting PPARγ, PPARα and PPARδ with IC50 of 3.3 nM, 32 nM and 2 μM, respectively.
DC2076	L-165041 Featured	L-165041 is a potent PPARδ agonist (Ki = 6 nM).
DC12034	MA-0204 Featured	MA-0204 is a potent, selective PPARδ modulator with good pharmacokinetic properties.
DC9897	Palmitoylethanolamide	Palmitoylethanolamide(PEA) is an endogenous fatty acid amide and selectively activates PPAR-α in vitro with an EC50 value of 3.1±0.4 μM.
DC11360	Pemafibrate Featured	Pemafibrate is an orally bioavailable and selective agonist of peroxisome proliferator-activated receptor α (PPARα; EC50 = 1 nM for transcriptional activity), a transcription factor that is essential for regulation of lipid homeostasis.
DCAPI1413	pioglitazone hydrochloride Featured	Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-activated receptor-γ). Pioglitazone is a thiazolidinedione compound described to produce antiinflammatory and antiarteri
DC11430	RB-394	RB394 is an orally bioavailable and dual modulator of soluble epoxide hydrolase (sEH) and PPARγ.
DCAPI1480	rosiglitazone maleate Featured	Rosiglitazone maleate is a potent and selective activator of PPARγ, with EC50s of 30 nM, 100 nM and 60 nM for PPARγ1, PPARγ2, and PPARγ, respectively, and a Kd of appr 40 nM for PPARγ; Rosiglitazone maleate is also an modulator of TRP channels, inhibits T
DC9084	Rosiglitazone base	Rosiglitazone(BRL-49653) is a high-affinity selective agonist of the peroxisome proliferator-activated receptor-γ(PPARγ).
DC10700	Seladelpar Featured	Seladelpar is a selective peroxisome proliferator-activated receptor (SPPAR) -δ receptor agonist.
DC9601	T0070907 Featured	T0070907 is a potent and selective PPARγ antagonist with IC50 of 1 nM; displays > 800-fold selectivity for PPARγ over PPARα and PPARδ.
DC8903	Troglitazone	Troglitazone(CS-045), PPARγ agonist, is an anti-diabetic thiazolidinedione (TZD) with anti-inflammatory and anti-tumor activity.
DC1034	WY14643 (Pirinixic Acid) Featured	WY 14643 (Pirinixic Acid) is a potent peroxisome proliferator and activator of PPARα with ED50 of 1.5 μM.
DC7412	R(+)-Etomoxir (sodium salt) Featured	A PPARα agonist and an irreversible CPT-1 inhibitor.
DC10320	Saroglitazar (Magnesium)	Saroglitazar magnesium is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.
DC10322	Saroglitazar	Saroglitazar is a novel peroxisome proliferator-activated receptor (PPAR) agonist with predominant PPARα and moderate PPARγ activity with EC50 values of 0.65 pM and 3 nM in HepG2 cells, respectively.

PPAR

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