| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11518 | Cavosonstat Featured | Cavosonstat is a potent, orally bioavailable inhibitor of S-nitrosoglutathione reductase (GSNOR) and CFTR modulator. |
|
| DC9986 | Acebilustat(ZK322) Featured | Acebilustat(ZK322) is a potent and selective leukotriene A4 hydrolase inhibitor. |
|
| DC10459 | BMS-986020 Featured | BMS-986020 is an LPA1 antagonist. |
|
| DC9278 | CWHM-12 Featured | CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1. |
|
| DC9434 | DMP 777 | DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor. |
|
| DC11803 | GLPG-1690(Ziritaxestat) Featured | GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM. |
|
| DC10753 | GLPG-1837(ABBV-974) Featured | GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator. |
|
| DC11678 | GLPG-2222 | GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM. |
|
| DC4128 | Ivacaftor (VX-770) Featured | Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. |
|
| DC11096 | Olacaftor | Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.. |
|
| DC11100 | PBI-4050 sodium | PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
|
| DC11099 | PBI-4050 | PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
|
| DC10390 | TD139 Featured | TD139 is a novel high-affinity inhibitor of the galectin-3 carbohydrate binding domain with a Kd of 14 nM. |
|
| DC1059 | Lumacaftor(vx-809，vx809) Featured | VX-809 is a CFTR modulator with EC50 of 0.1 μM. |
|
