Cat. No. | Product name | CAS No. |
DC11518 |
Cavosonstat
Featured
Cavosonstat is a potent, orally bioavailable inhibitor of S-nitrosoglutathione reductase (GSNOR) and CFTR modulator. |
1371587-51-7 |
DC9986 |
Acebilustat(ZK322)
Featured
Acebilustat(ZK322) is a potent and selective leukotriene A4 hydrolase inhibitor. |
943764-99-6 |
DC10459 |
BMS-986020
Featured
BMS-986020 is an LPA1 antagonist. |
1257213-50-5 |
DC9278 |
CWHM-12
Featured
CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1. |
1564286-55-0 |
DC9434 |
DMP 777
DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor. |
157341-41-8 |
DC11803 |
GLPG-1690(Ziritaxestat)
Featured
GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM. |
1628260-79-6 |
DC10753 |
GLPG-1837(ABBV-974)
Featured
GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator. |
1654725-02-6 |
DC11678 |
GLPG-2222
GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM. |
1918143-53-9 |
DC4128 |
Ivacaftor (VX-770)
Featured
Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively. |
873054-44-5 |
DC11096 |
Olacaftor
Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis.. |
1897384-89-2 |
DC11100 |
PBI-4050 sodium
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
1254472-97-3 |
DC11099 |
PBI-4050
PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively. |
1002101-19-0 |
DC10390 |
TD139
Featured
TD139 is a novel high-affinity inhibitor of the galectin-3 carbohydrate binding domain with a Kd of 14 nM. |
1450824-22-2 |
DC1059 |
Lumacaftor(vx-809,vx809)
Featured
VX-809 is a CFTR modulator with EC50 of 0.1 μM. |
936727-05-8 |