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Anemia

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Cat. No. Product Name Field of Application Chemical Structure
DC11607 JTZ-951(Enarodustat) Featured A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2.
DC11608 JTZ-951 hydrochloride A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2.
DC8188 Daprodustat Featured Daprodustat(GSK1278863) isa HIF-prolyl hydroxylase inhibitor.
DC5193 Roxadustat(FG-4592) Featured FG-4592 is an HIF αprolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production.
DC10474 GBT-440(Voxelotor) Featured GBT-440(Voxelotor) is a novel small molecule hemoglobin modifier which increases hemoglobin oxygen affinity.
DC8166 Molidustat(BAY 85-3934) Featured Hypoxia-inducible factor prolyl hydroxylase inhibitor
DC10339 Vadadustat Featured Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.

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