| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC9137 | Timolol Maleate Featured | (S)-Timolol maleate, is a potent non-selective β-adrenergic receptor antagonist (Ki values are 1.97 and 2.0 nM for β1 and β2 receptor subtypes respectively). |
|
| DCAPI1496 | Ambrisentan Featured | A nonpeptide endothelin ETA receptor antagonist. Antihypertensive. |
|
| DC11893 | Firibastat | A potent, orally active, centrally acting aminopeptidase inhibitor, the prodrug of the specific and selective aminopeptidase A inhibitor EC33. |
|
| DC11850 | MK-7145 | A potent, selective, and oral renal outer medullary potassium channel (ROMK) inhibitor with IC50 of 68 nM. |
|
| DCAPI1495 | Aliskiren Hemifumarate Featured | Aliskiren hemifumarate(CGP 60536) is a direct renin inhibitor with IC50 of 1.5 nM. |
|
| DC9020 | Atenolol | Atenolol is a selective β1 receptor antagonist. |
|
| DC4210 | Azilsartan kamedoxomil Featured | Azilsartan medoxomil is an angiotensin II receptor antagonist indicated for the treatment of mild to moderate essential hypertension. |
|
| DCAPI1469 | azilsartan Featured | Azilsartan(TAK-536) is a specific and potent angiotensin II type 1 receptor antagonist with IC50 of 2.6 nM. |
|
| DC9185 | Candesartan cilexetil Featured | Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. |
|
| DC9142 | Candesartan | Candesartan is an angiotensin II receptor antagonist with IC50 of 0.26 nM. |
|
| DC8471 | CGS 21680 hydrochloride Featured | CGS 21680 hydrochloride is an A2A adenosine receptor agonist (Ki = 27 nM). |
|
| DC9160 | Cilnidipine Featured | Cilnidipine(FRC8653) is a dual L- and N-type calcium channel blocker and displays antihypertensive, sympatholytic and neuroprotective activity. |
|
| DC9380 | Cleviprex Featured | Clevidipine(Clevidipine) is a short-acting dihydropyridine calcium channel antagonist (IC50= 7.1 nM, V(H) = -40 mV ) under development for treatment of perioperative hypertension. |
|
| DCAPI1152 | Diltiazem HCl (Tiazac) | Diltiazem HCl (Tiazac) |
|
| DC10446 | (3R,4S,5S)-tert-butyl 3-Methoxy-5-Methyl-4-(MethylaMino)heptanoate hydroc hloride Featured | Diltiazem hydrochloride is a calcium ion influx inhibitor (slow channel blocker or calcium antagonist). |
|
| DCAPI1596 | Metroprolol succinate | For the detailed information of Metroprolol succinate, the solubility of Metroprolol succinate in water, the solubility of Metroprolol succinate in DMSO, the solubility of Metroprolol succinate in PBS buffer, the animal experiment (test) of Metroprolol succinate, the cell expriment (test) of Metroprolol succinate, the in vivo, in vitro and clinical trial test of Metroprolol succinate, the EC50, IC50,and Affinity of Metroprolol succinate, Please contact DC Chemicals.. |
|
| DC10233 | Guanfacine Hydrochloride | Guanfacine Hydrochloride is a selective α2A-adrenoceptor agonist with anti-hypertensive effect. |
|
| DC9123 | Lisinopril Dihydrate | Lisinopril Dihydrate is angiotensin-converting enzyme inhibitor, used in treatment of hypertension, congestive heart failure, and heart attacks. |
|
| DCAPI1419 | Losartan | Losartan is a potent, non peptide antagonist of the angiotensin II receptor type 1. This receptor initiates a signal cascade that causes vasoconstriction. Antagonism of this receptor in turn causes vasodilation by blocking the signal from angiotensin II. |
|
| DC9153 | Losartan Potassium Featured | Losartan is an angiotensin II receptor antagonist, competes with the binding of angiotensin II to AT1 receptors with IC50 of 20 nM. |
|
| DC9190 | Manidipine Dihydrochlorid | Manidipine 2Hcl (CV-4093) is a dihydropyridine compound and a calcium channel blocker for Ca2+ current with IC50 of 2.6 nM. |
|
| DC11315 | Manidipine(CV-4093) | Manidipine is a dihydropyridine L- and T-type calcium channel blocker. |
|
| DC9191 | Metoprolol tartrate | Metoprolol is a cardioselective β1-adrenergic blocking agent. |
|
| DC5177 | Nepicastat HCl (SYN-117) Featured | Nepicastat hydrochloride is a potent and selective inhibitor of both bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors. |
|
| DC9170 | Nicardipine hydrochloride | Nicardipine Hcl(YC-93) is a calcium channel blocker that has been widely used to control blood pressure in severe hypertension following events such as ischemic stroke, traumatic brain injury, and intracerebral hemorrhage. |
|
| DC9108 | Nisoldipine | Nisoldipine(BAY-k 5552; Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM. |
|
| DCAPI1464 | Olmesartan | Olmesartan Acid is an angiotensin II receptor antagonist that prevents the binding of angiotensin II, thus preventing vasoconstriction. |
|
| DC9179 | Olmesartan MedoxoMil | Olmesartan medoxomil(Olmetec; Benicar; CS 866) is an angiotensin II receptor antagonist which is used as an anti-hypertensive. |
|
| DC10324 | Omapatrilat | Omapatrilat is a dual inhibitor of the metalloproteases ACE and NEP with Ki values of 0.64 and 0.45 nM, respectively. |
|
| DC11138 | Guanabenz acetate | R15A inhibitor. |
|
