Cat. No. | Product name | CAS No. |
DC11886 |
Adavivint
Featured
Adavivint (SM-04690, SM 04690, SM04690) is a novel small molecule Wnt pathway inhibitor with EC50 of 3 nM in vitro |
1467093-03-3 |
DC9406 |
Ampiroxicam
Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. |
99464-64-9 |
DC5014 |
AVL-292
Featured
AVL-292 is a covalent, highly selective, orally active small molecule inhibitor of Btk currently being evaluated in a Phase 1b clinical trial in relapsed. |
1202757-89-8 |
DC10425 |
AZD9056 hydrochloride
AZD9056 is a selective orally active inhibitor of P2X7 which plays a significant role in inflammation and pain-causing diseases. |
345303-91-5 |
DC11541 |
AZD-9567
AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis.. |
1893415-00-3 |
DC11542 |
AZD-9567 monohydrate
AZD-9567 (AZD9567) is a potent, selective, non-steroidal and orally available selective glucocorticoid receptor modulator (SGRM) for treatment of rheumatoid arthritis.. |
1893415-64-9 |
DC11819 |
BMS-986142
Featured
BMS-986142 is a potent, selective, and reversible BTK (Bruton’s tyrosine kinase) inhibitor (BTK IC₅₀ = 0.5nM; human WB IC₅₀ = 90 nM). |
1643368-58-4 |
DC12030 |
BMS-986195
Featured
BMS-986195 is a potent, covalent, irreversible inhibitor of Bruton’s tyrosine kinase (BTK). |
1912445-55-6 |
DC11154 |
CR6086
CR6086 (CR-6086) is a potent, selective prostaglandin E2 receptor 4 (EP4) antagonist with Ki of 16.6 nM (hEP4 receptor), inhibits PGE2-stimulated cAMP production with IC50 of 22 nM. |
|
DC8171 |
Decernotinib (VX-509,adelatinib)
Featured
Decernotinib(VX-509; VRT-831509) is a potent and selective Janus kinase 3 (JAK3) inhibitor with Ki of 2.5 nM; IC50 is 50-170 nM in cellular assays. |
944842-54-0 |
DC11398 |
Edicotinib(JNJ-40346527)
Featured
Edicotinib(JNJ-40346527)is a small molecule and orally available inhibitor of colony-stimulating factor-1 receptor (CSF1R; FMS) with potential antineoplastic activity. |
1142363-52-7 |
DC10380 |
Evobrutinib
Featured
Evobrutinib is an inhibitor of Bruton's tyrosin kinase (Btk) inhibitor extracted from patent US20140162983 example 0174. |
1415823-73-2 |
DC9942 |
GDC-0853(RG7845)
Featured
GDC-0853 is orally available inhibitor of Bruton's tyrosine kinase (BTK) with potential antineoplastic activity. |
1434048-34-6 |
DC7137 |
Filgotinib(GLPG0634)
Featured
GPLG0634 is a novel inhibitor of JAK1 and JAK2 with IC50 of 10nM and 28nM respectively. |
1206161-97-8 |
DC9715 |
CHR5154
Featured
GSK3117391 (CHR5154) is a HDAC inhibitor. |
1018673-42-1 |
DC8872 |
Iguratimod
Featured
Iguratimod is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. |
123663-49-0 |
DC9389 |
INCB3344
INCB3344 is a novel, potent and selective small molecule antagonist of the mouse CCR2 receptor; inhibits the binding of CCL2 to mouse monocytes with nanomolar potency (IC50 = 10 nM). |
1262238-11-8 |
DC9011 |
Mizoribine
Featured
Mizoribine(NSC 289637; HE 69; β-Bredinin) is an immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH. |
50924-49-7 |
DC9681 |
Pamapimod(R-1503)
Featured
Pamapimod(R-1503)is a novel p38 MAP kinase inhibitor. |
449811-01-2 |
DC8168 |
Peficitinib(ASP015K,JNJ-54781532)
Featured
Peficitinib(ASP015K,JNJ-54781532) is a novel potent JAK inhibitor, which demonstrated potent efficacy in adjuvant-induced arthritis model in rats. |
944118-01-8 |
DC10779 |
PF-06651600
Featured
PF-06651600 is a potent JAK3-selective inhibitor with an IC50 of 33.1 nM. |
1792180-81-4 |
DC11373 |
Polmacoxib
Polmacoxib is an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrase subtypes I (CAI) and CAII. |
301692-76-2 |