| DC7961 |
(-)MK-801 maleate
Featured
|
(-)-MK 801 Maleate is the enantiomer of (+)-MK-801; (+)-MK-801 is a highly potent and selective non-competitive NMDA glutamate receptor antagonist . |
|
| DC10801 |
AMPA/kainate antagonist-1
Featured
|
A novel Non-competitive AMPA/kainate antagonist. |
|
| DC10808 |
AMPA/kainate antagonist-3
Featured
|
A novel Non-competitive AMPA/kainate antagonist. |
|
| DC10802 |
AMPA/kainate antagonist-2 |
A novel Non-competitive AMPA/kainate antagonist. |
|
| DC5075 |
BDP-12(Ampalex)
Featured
|
Ampalex (Ampakine CX516) is an ampakine and nootropic that acts as an AMPA receptor positive allosteric modulator as a treatment for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI). |
|
| DC8976 |
Aniracetam |
Aniracetam(Ro 13-5057) is a nootropics and neuroprotective drug, which is selectively modulates the AMPA receptor and nAChR. |
|
| DC9340 |
CFM-2 |
CFM-2 is a selective non-competitive AMPAR antagonist.
|
|
| DC9849 |
CGP37849 |
CGP37849 is a potent, selective and competitive NMDA receptor antagonist (Ki = 35 nM). Anticonvulsive following oral administration in vivo. |
|
| DC8156 |
CIQ
Featured
|
CIQ is a positive allosteric modulator selective for NR2C/D containing NMDA receptors (EC50 = 2.7 and 2.8 µM for NR2C and NR2D, respectively). |
|
| DC10671 |
CNQX disodium salt
Featured
|
CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex. |
|
| DC10670 |
CNQX
Featured
|
CNQX is a potent AMPA/kainate receptor antagonist. Also antagonist at glycine modulatory site on NMDA receptor complex. |
|
| DC8543 |
CP465022 HCl |
CP 465022 hydrochloride is a selective GluR (AMPA) antagonist which is non-competitive. |
|
| DC7960 |
(+)MK-801 maleate
Featured
|
Dizocilpine maleate(MK 801) is a potent N-methyl-D-aspartate (NMDA) receptor antagonist with Ki of 30.5 nM |
|
| DC9250 |
DL-AP7
Featured
|
DL-AP7 is a competitive antagonist of the ionotropic glutamate receptor, NMDA. |
|
| DC10673 |
DNQX disodium salt
Featured
|
DNQX is a elective non-NMDA antagonist |
|
| DC10672 |
DNQX
Featured
|
DNQX is a elective non-NMDA antagonist |
|
| DC8268 |
Eliprodil
Featured
|
Eliprodil is a non-competitive NMDA receptor antagonist that acts at the polyamine modulatory site. |
|
| DC9893 |
Evans Blue |
Evans Blue is a potent inhibitor of the uptake of L-glutamate into synaptic vesicles, also an AMPA/kainate receptor antagonist |
|
| DC10382 |
Farampator
Featured
|
Farampator (CX-691;Org24448) is an AMPA receptor positive modulator. |
|
| DC5061 |
GYKI 52466 dihydrochloride |
GYKI 52466 dihydrochloride is a selective non-competitive AMPA receptor antagonist (IC50 values are 10-20, ~ 450 and >> 50 μM for AMPA- , kainate- and NMDA-induced responses respectively). Skeletal muscle relaxant and orally-active anticonvulsant. |
|
| DC8769 |
IEM 1754 DihydrobroMide |
IEM 1754 2HBr is a selective AMPA/kainate receptor blockers for GluR1 and GluR3 with IC50 of 6 μM. |
|
| DC11229 |
JNJ-55511118 |
JNJ-55511118 (JNJ55511118) is a selective, orally available AMPA receptor containing TARP-γ8 negative modulator with Ki of 26 nM, displays no significant activity against other TARP-less AMPARs and AMPARs coexpressed with other TARPs or CNIH2. |
|
| DC8159 |
L-701,324
Featured
|
L-701,324 is a selective antagonist at the glycine site of the NMDA receptor, counteracts haloperidol-induced muscle rigidity in rats. |
|
| DC7194 |
MDL 29951
Featured
|
MDL-29951 is a novel glycine antagonist of NMDA receptor activation (Ki=0.14 mM, [3H]glycine binding) in vitro and in vivo. |
|
| DC9341 |
Naspm
Featured
|
Naspm(1-Naphthylacetyl spermine) is a potent and selective Ca2+ permeable AMPA receptor(Ca-perm AMPAR) blocker.
IC50 value:
Target: CP-AMPAR blocker
Naspm is a selective blocker of Ca(2+)-permeable GluA2-lacking AMPA receptors, reduced MNNG-induced CA1 |
|
| DC11406 |
NBQX
Featured
|
NBQX is a potent aminomethylphosphonic acid receptor (AMPAR) antagonist with an IC50 of 0.7 ± 0.1 μM. |
|
| DC7576 |
NVP-AAM077
Featured
|
NVP-AAM077 is a potent antagonist for NMDA receptors. |
|
| DC11382 |
NYX-2925
Featured
|
NYX-2925 is a Novel NMDA Receptor-Specific Spirocyclic-β-Lactam That Modulates Synaptic Plasticity Processes Associated with Learning and Memory. |
|
| DC10394 |
Org-26576 |
Org 26576 is a AMPA receptor positive allosteric modulator. |
|
| DC7989 |
PEPA
Featured
|
PEPA is an allosteric modulator of AMPA receptors; binds to the GluA2o and GluA3o LBDs and can be utilized as an indicator of AMPA receptor heterogeneity. |
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