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Cat. No. Product name CAS No.
DC11066 MALT1 paracaspase inhibitor 3

MALT1 paracaspase inhibitor 3 is a potent, specific, covalent inhibitor of MALT1 paracaspase with Ki of 10 nM, exhibits 10-and 100-fold improved potency in vitro and in vivo compared with Z-VRPR-fmk.

2088355-90-0
DC9503 MI 2 (MALT1 inhibitor) Featured

MI 2(MALT1 inhibitor) is a small molecule and irreversible inhibitor of MALT1 with IC50 of 5.84 uM(suppression of proliferation in ABCDLBCL).

1047953-91-2
DC7621 MI 2 (Menin-MLL Inhibitor) Featured

MI-2 is an inhibitor of MALT1 with IC50 value of 5.84 μM.

1271738-62-5
DC40281 Mepazine hydrochloride

Mepazine hydrochloride (Pecazine hydrochloride) is a potent and selective MALT1 protease inhibitor with IC50s of 0.83 and 0.42 μM for GSTMALT1 full length and GSTMALT1 325-760, respectively. Mepazine hydrochloride affects viability of ABC-DLBCL cells by enhancing apoptosis.

2975-36-2
DC42356 MLT-231

MLT-231 is a potent, highly selective allosteric MALT1 with an IC50 of 9 nM. MLT-231 specifically prevents endogenous BCL10 cleavage with IC50 of 160 nM. MLT-231 shows antitumor activity in an ABC-DLBCL type xenograft model in mouse.

DC46393 JNJ-67856633 Featured

JNJ-67856633 is an orally active, first-in-class, potent, selective and allosteric MALT1 protease inhibitor. JNJ-67856633 in some cases lead to tumor stasis.

2230273-76-2
DC46605 Z-VRPR-FMK TFA

Z-VRPR-FMK (TFA) (VRPR), a tetrapeptide, is a selective and irreversible MALT1 (Mucosa-associated lymphoid tissue lymphoma translocation protein 1) inhibitor. Z-VRPR-FMK (TFA) can protect against influenza A virus (IAV) infection.

DC48250 MLT-985

MLT-985 is a highly selective allosteric MALT1 inhibitor with an IC50 value of 3 nM.

1832576-25-6
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