| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC7804 | Anacetrapib(MK0859) Featured | Anacetrapib (MK0859) is a potent, selective, reversible rhCETP and mutant CETP(C13S) inhibitor with IC50 of 7.9 nM and 11.8 nM, increases HDL-C and decreases LDL-C, does not increase aldosterone or blood pressure. Phase 3. |
|
| DC9861 | BMS-779788(XL-652) Featured | BMS-779788(XL652) is a novel small-molecule modulator of the Liver X Receptor (LXR), a nuclear hormone receptor implicated in a variety of cardiovascular and metabolic disorders. |
|
| DC7397 | Darapladib Featured | Darapladib is a selective and orally active inhibitor of Lp-PLA2 (IC50= 270 pM) |
|
| DC2072 | LXR623 Featured | LXR-623 is a novel Liver X Receptor modulator |
|
| DC9456 | MK-0354 | MK-0354 is a partial agonist of GPR109a receptor, for hGPR109a/ mGPR109a with EC50 of 1.65/1.08 μM, showed no activation of GPR109b. |
|
| DC9609 | Terutroban Featured | Terutroban is a thromboxane/prostaglandin endoperoxide receptor antagonist. |
|
| DC7519 | Torcetrapib Featured | Torcetrapib is a CETP inhibitor with IC50 of 37 nM, elevates HDL-C and reduces nonHDL-C in plasma. Phase 3. |
|
