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Cat. No. Product name CAS No.
DC9450 (R)-Baclofen

(R)-Baclofen(STX209) is a selective GABAB receptor agonist.

69308-37-8
DCE-016 Chenodeoxycholic acid

>98%,Standard References

474-25-9
DC11919 Arimoclomol Featured

A nontoxic heat shock protein (HSP) coinducer and potentiator of the heat shock response.

289893-25-0
DC11920 Arimoclomol maleate Featured

A nontoxic, orally active heat shock protein (HSP) coinducer and potentiator of the heat shock response.

289893-26-1
DC11515 Azeloprazole

A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.

955095-45-1
DC11607 JTZ-951(Enarodustat) Featured

A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2.

1262132-81-9
DC11608 JTZ-951 hydrochloride

A novel potent, orally active HIF prolyl hydroxylase (PHD) inhibitor with IC50 of 0.22 uM for PHD2.

1262131-60-1
DC11546 Azeloprazole sodium

A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM.

955095-47-3
DC11533 PH-46A N-Methyl-D-Glucamine salt

A potent, first-in-class, oral small-molecule agent for the treatment of inflammatory bowel diseases..

1380445-04-4
DC11532 PH-46A

A potent, first-in-class, oral small-molecule agent for the treatment of inflammatory bowel diseases..

1421332-97-9
DC11518 Cavosonstat Featured

Cavosonstat is a potent, orally bioavailable inhibitor of S-nitrosoglutathione reductase (GSNOR) and CFTR modulator.

1371587-51-7
DC11519 Ceclazepide

A potent, selective cholecystokinin receptor CCK2 antagonist for treatment of gastroesophageal reflux disease (GERD)..

1801749-44-9
DC11688 Avacopan Featured

Avacopan is a potent, selective, orally availale C5aR (CD88) inhibitor with IC50 of 0.1 nM.

1346623-17-3
DC11525 Mocravimod

A synthetic immunosuppressant that functions as a S1P1 receptor agonist.

509092-16-4
DC9986 Acebilustat(ZK322) Featured

Acebilustat(ZK322) is a potent and selective leukotriene A4 hydrolase inhibitor.

943764-99-6
DC11512 Acrizanib Featured

Acrizanib(LHA510) is a potent and selective angiogenesis inhibitor and VEGFR‑2 Inhibitor Specifically Designed for Topical Ocular Delivery, as a Therapy for Neovascular Age-Related Macular Degeneration.

1229453-99-9
DC10234 Alosetron Hydrochloride

Alosetron Hydrochloride is the hydrochloride salt form of alosetron, a potent and selective 5-HT3 receptor antagonist.

122852-69-1
DC8606 Alvimopan monohydrate

Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.

1383577-62-5
DC8605 Alvimopan dihydrate

Alvimopan(LY 246736; ADL 8-2698) is a peripherally acting mu-opioid receptor (PAM-OR, IC50= 1.7 nM) antagonist for accelerating gastrointestinal recovery after surgery.

170098-38-1
DC11076 Ampreloxetine

Ampreloxetine (TD-9855) is a potent monoamine reuptake inhibitor with pIC50 of 8.0, 8.6 and 6.8 for human NET, SERT, and DAT, respectively.

1227056-84-9
DC9034 Atomoxetine HCl

Atomoxetine Hcl(LY 139603; Tomoxetine Hcl) is a potent and selective noradrenalin re-uptake inhibitor (Ki values are 5, 77 and 1451 nM for inhibition of radioligand binding to human NET, SERT and DAT respectively).

82248-59-7
DC8971 Baclofen

Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a skeletal muscle relaxant.

1134-47-0
DC8895 benzbromaron Featured

Benzbromarone is a highly effective and well tolerated non-competitive inhibitor of xanthine oxidase, used as an uricosuric agent, used in the treatment of gout.

3562-84-3
DC10459 BMS-986020 Featured

BMS-986020 is an LPA1 antagonist.

1257213-50-5
DC11354 Carteolol (hydrochloride)

Carteolol is an antagonist of β-adrenergic receptors (Kd = 13 nM).

51781-21-6
DC4160 CB-03-01 Featured

CB-03-01 is a steroidal ester, androgen antagonist derived from 11-deoxycortisone, which tightly mimics the profile of an ideal anti-androgen for topical use.

19608-29-8
DC10868 Cilofexor Featured

Cilofexor (GS-9674, GS9674) is novel specific, non-steroidal farnesoid X receptor (FXR) agonist that reduces liver fibrosis and ameliorates portal hypertension in rat NASH models.

1418274-28-8
DC9183 Clomiphene citrate

Clomifene Citrate is a selective estrogen receptor modulator.

50-41-9
DCAPI1091 Conivaptan hydrochloride Featured

Conivaptan(YM 087) is a non-peptide inhibitor of antidiuretic hormone (vasopressin receptor antagonist) with Ki values of 0.48 and 3.04 nM for rat liver V1A receptor and rat kidney V2 receptor respectively.

168626-94-6
DC4132 CP-547632 Featured

CP-547632 is as a potent inhibitor of the VEGFR-2 and basic fibroblast growth factor (FGF) kinases (IC50 11 and 9 nM, respectively).

252003-65-9
DC9278 CWHM-12 Featured

CWHM-12 a novel small molecule inhibitor of αV integrins with IC50s of 1.8/0.8/1.5/0.2 nM for αvβ1/αvβ3/αvβ8; less potency on αvβ5(IC50=61 nM) and on inhibition on αIIbβ3/α2β1/α10β1.

1564286-55-0
DC11082 Danicopan (ACH-4471) Featured

Danicopan (ACH-4471, ACH-0144471) is a highly potent, orally active Factor D inhibitor with Kd of 0.54 nM, inhibits the proteolytic activity of purified Factor D against substrate Factor B in complex with C3b, blocking production of Bb fragment IC50 of 15 nM.

1903768-17-1
DC9116 Dantrolene sodium

Dantrolene sodium is a inhibitor of calcium channel proteins, inhibiting the release of Ca2+ from the sarcoplasm. Dantrolene sodium is a skeletal muscle relaxant which acts by blocking muscle contraction beyond the neuromuscular junction.

14663-23-1
DC8188 Daprodustat Featured

Daprodustat(GSK1278863) isa HIF-prolyl hydroxylase inhibitor.

960539-70-2
DCAPI1107 Deferasirox (Exjade) Featured

Deferasirox (Exjade)

201530-41-8
DC9604 Desogestrel Featured

Desogestrel(Org-2969) is a third-generation 19-nortestosterone derivative progestogen; is contained in many oral contraceptive preparations, both combined (COCs) to ethinyl-estradiol (EE) or alone in a progestin-only pill (POP).

54024-22-5
DC9434 DMP 777

DMP 777(L-694458) is a potent, selective, and orally active human leukocyte elastase (HLE) inhibitor.

157341-41-8
DC8485 E-64d(Aloxistatin) Featured

E-64D is an inhibitor of cathepsins B and L; also thought to inhibit calpain,showed a potent activity for COVID-19(SARS-COV-2)with EC50: MERS-COV(1.275),SARS-COV(0.760)

88321-09-9
DC10939 Edasalonexent

Edasalonexent (CAT-1004) is a bifunctional, orally administered small molecule that covalently links 2 compounds known to inhibit NF‐κB, salicylic acid and docosahexaenoic acid (DHA).

1204317-86-1
DC8626 Eluxadoline Featured

Eluxadoline is an orally active mixed μ opioid receptor (μOR) agonist δ opioid receptor (δOR) antagonist.

864821-90-9
DC9771 ACU4429,ACU 4429,ACU-4429 Featured

Emixustat hydrochloride strongly inhibits 11-cis-retinol production with IC50 values of 232 ± 3 nM.

1141934-97-5
DC10314 Emixustat

Emixustat, a novel visual cycle modulator, is an inhibitor of the visual cycle isomerase with an IC50 value of 4.4 nM in vitro.

1141777-14-1
DC9762 Emricasan Featured

Emricasan (IDN-6556, PF-03491390) is a potent irreversible pan-caspase inhibitor.

254750-02-2
DC11433 Vatiquinone

EPI-743 (Vatiquinone,EPI-589) is an orally bioavailable para-benzoquinone for treatment of inherited mitochondrial diseases, an analogue of the antioxidant ubidecarenone.

1213269-98-7
DC10040 Etrasimod(APD334) Featured

Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1(S1P1) receptor with an IC50 value of 1.88 nM in CHO cells.

1206123-37-6
DC9821 Ezutromid Featured

Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM .

945531-77-1
DC8912 Fesoterodine fumarate Featured

Fesoterodine Fumarate is an antimuscarinic agent and is rapidly de-esterified to its active metabolite 5-hydroxymethyl tolterodine that is a muscarinic receptor antagonist.

286930-03-8
DC5193 Roxadustat(FG-4592) Featured

FG-4592 is an HIF αprolyl hydroxylase inhibitor, stabilizes HIF-2 and induces EPO production.

808118-40-3
DC11187 Fonadelpar

Fonadelpar (NPS-005,SJP-0035) is a potent, selective peroxisome proliferator activated receptor δ (PPARδ) agonist for the treatment of corneal disorders..

515138-06-4
DC6917 Vonoprazan Featured

For the detailed information of Vonoprazan, the solubility of Vonoprazan in water, the solubility of Vonoprazan in DMSO, the solubility of Vonoprazan in PBS buffer, the animal experiment (test) of Vonoprazan, the cell expriment (test) of Vonoprazan, the in vivo, in vitro and clinical trial test of Vonoprazan, the EC50, IC50,and affinity,of Vonoprazan, For the detailed information of Vonoprazan, the solubility of Vonoprazan in water, the solubility of Vonoprazan in DMSO, the solubility of Vonoprazan in PBS buffer, the animal experiment (test) of Vonoprazan, the cell expriment (test) of Vonoprazan, the in vivo, in vitro and clinical trial test of Vonoprazan, the EC50, IC50,and affinity,of Vonoprazan, Please contact DC Chemicals..

881681-00-1
DC11394 Fulacimstat(BAY 1142524) Featured

Fulacimstat(BAY 1142524) is a small molecule chymase inhibitor.

1488354-15-9
DC9859 GAL-021 Featured

GAL-021 is a new intravenous BKCa-channel blocker.

1380341-99-0
DC10474 GBT-440(Voxelotor) Featured

GBT-440(Voxelotor) is a novel small molecule hemoglobin modifier which increases hemoglobin oxygen affinity.

1446321-46-5
DC11803 GLPG-1690(Ziritaxestat) Featured

GLPG-1690 is a first-in-class, potent, competitive autotaxin inhibitor with Ki/IC50 of 15 nM/131 nM.

1628260-79-6
DC10753 GLPG-1837(ABBV-974) Featured

GLPG-1837(ABBV-974) is a novel cystic fibrosis transmembrane conductance regulator CFTR potentiator.

1654725-02-6
DC11678 GLPG-2222

GLPG-2222 (ABBV-2222, Galicaftor) is a novel potent and efficacious CFTR corrector with EC50 of 5 nM.

1918143-53-9
DC9738 GSK2881078 Featured

GSK2881078 (GSK-2881078 ) is a selective androgen receptor modulator (SARM).

1539314-06-1
DC10936 GSK3179106 Featured

GSK3179106 (GSK-3179106, GSK 3179106) is a potent, selective, first-in-class and gut-restricted with IC50 of 0.4 and 11 nM in the biochemical assay and cellular assay respectively.

1627856-64-7
DC8166 Molidustat(BAY 85-3934) Featured

Hypoxia-inducible factor prolyl hydroxylase inhibitor

1154028-82-6
DC10007 Ibiglustat(Genz-682452) Featured

Ibiglustat (Genz-682452,SAR402671), is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor.

1401090-53-6
DC10205 Ilaprazole Featured

Ilaprazole (IY-81149) is a proton pump inhibitor; inhibits H+/K+-ATPase with an IC50 of 6.0 μM.

172152-36-2
DC7430 Obeticholic acid (INT-747) Featured

INT-747(Obeticholic acid; 6-ECDCA) is a potent and selective FXR agonist(EC50=99 nM) endowed with anticholestatic activity.

459789-99-2
DC7172 IOWH-032

iOWH032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays.

1191252-49-9
DC4128 Ivacaftor (VX-770) Featured

Ivacaftor (VX-770, Kalydeco) is a potentiator of CFTR targeting G551D-CFTR and F508del-CFTR with EC50 of 100 nM and 25 nM, respectively.

873054-44-5
DC12374 JNJ-10229570 Featured

JNJ-10229570 (JNJ10229570) is a novel potent, selective melanocortin receptor MC1R and MC5R antagonist with binding IC50 of 270 nM and 200 nM, respectively.

524923-88-4
DC10853 LAU159 Featured

LAU159 is a novelα6β3γ2 GABAA receptor inhibitor.

2055050-87-6
DC12386 Leniolisib (CDZ173) Featured

Leniolisib (CDZ173) is a potent and selective PI3Kδ inhibitor currently in phase II/III clinical trials for the treatment of immunodeficiency disorders.

1354690-24-6
DC7633 Ligandrol (VK5211, LGD-4033) Featured

LGD-4033 is a novel selective androgen receptor modulator (SARM)

1165910-22-4
DC9938 Lusutrombopag(S-888711) Featured

Lusutrombopag(S-888711) is an orally bioavailable, small molecule thrombopoietin (TPO) receptor agonist being developed by Shionogi for chronic liver disease (CLD) patients with thrombocytopenia prior to elective invasive surgery.

1110766-97-6
DC11524 Mavacamten(MYK-461) Featured

Mavacamten(MYK-461)is a small molecule that reduces contractility by decreasing the ATPase activity of the cardiac myosin heavy chain.

1642288-47-8
DC9527 Methylnaltrexone (Bromide) Featured

Methylnaltrexone Bromide is a pheriphally-acting μ-opioid antagonist that acts on the gastrointestinal tract to decrease opioid-induced constipation.

73232-52-7
DC9995 MGL-3196(Resmetirom) Featured

MGL-3196 is a potent and highly selective thyroid hormone receptor β agonist in clinical trials for the treatment of dyslipidemia.

920509-32-6
DC10326 Mozavaptan

Mozavaptan (OPC31260) is a orally effective, nonpeptide vasopressin V2 receptor antagonist with an IC50 of 14 nM.

137975-06-5
DC10173 Firsocostat(ND-630,GS-0976) Featured

ND-630 is an acetyl-CoA carboxylase (ACC) inhibitor; inhibits human ACC1 and ACC2 with IC50 values of 2.1 and 6.1 nM, respectively.

1434635-54-7
DCAPI1342 Nepafenac

Nepafenac

78281-72-8
DC9520 NKP608

NKP608 is a non-peptidic derivative of 4-aminopiperidine which acts as a selective, specific and potent antagonist at the neurokinin-1 (NK-1) receptor both in vitro(IC50=2.6 nM) and in vivo.

177707-12-9
DC12298 Octreotide acetate (SMS 201-995 (acetate)) Featured

Octreotide acetate, a long-acting synthetic analog of native somatostatin, inhibits growth hormone, glucagon, and insulin more potently.

79517-01-4
DC11096 Olacaftor

Olacaftor (VX-440, VX440) is a next-generation CFTR corrector, showsthe potential to enhance the amount of CFTR protein at the cell’s surface and for treatment of cystic fibrosis..

1897384-89-2
DC8390 Oltipraz Featured

Oltipraz is a potent Nrf2 activator and a potent inducer of Phase II detoxification enzymes, most notably glutathione-S-transferase (GST). Phase 3.

64224-21-1
DC10299 Olumacostat glasaretil

Olumacostat glasaretil is a small molecule inhibitor of acetyl coenzyme A carboxylase (ACC).

1261491-89-7
DC11044 Omidenepag Isopropyl Featured

Omidenepag Isopropyl (DE-117, OMDI) is the prodrug of Omidenepag, which is a potent, selective agonist human EP2 receptor; demonstrates excellent IOP-lowering activities following ocular administration in ocular normotensive monkeys, Omidenepag Isopropyl (OMDI) is a clinical candidate for the treatment of glaucoma.

1187451-19-9
DC9876 Pantoprazole

Pantoprazole is a proton pump inhibitor used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

102625-70-7
DC9135 Pantoprazole Sodium

Pantoprazole sodium salt(SKF96022; Protonix) is a proton pump inhibitor drug used for short-term treatment of erosion and ulceration of the esophagus caused by gastroesophageal reflux disease.

138786-67-1
DC11100 PBI-4050 sodium

PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.

1254472-97-3
DC11099 PBI-4050

PBI-4050 (Setogepram, PBI4050) is a synthetic analog of a medium-chain fatty acid that displays agonist and antagonist ligand affinity toward GPR40 and GPR84, respectively.

1002101-19-0
DC8353 PF-04418948 Featured

PF-04418948 is an orally active, potent, and selective EP2 receptor antagonist (IC50 = 16 nM).

1078166-57-0
DCAPI1305 Pramiracetam

Pramiracetam

68497-62-1
DC9162 Ranolazine HCl Featured

Ranolazine(RS-43285) is an antianginal agent with antiarrhythmic properties that achieves its effects via a novel mechanism of action (inhibition of the late phase of the inward sodium current), without affecting heart rate or blood pressure (BP).

95635-56-6
DC1048 Rapamycin (Sirolimus) Featured

Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. -

53123-88-9
DC8185 Verosudil(AR-12286)

Rho-kinase (ROCK) inhibitor

1414854-42-4
DC10583 RO 5028442 Featured

RO5028442 is a highly potent and selective Brain-Penetrant Vasopressin 1a (V1a) receptor antagonist with Kis of 1 nM (hV1a) and 39 nM (mV1a).

920022-47-5
DC8198 RTA-408(Omaveloxolone) Featured

RTA-408 is a synthetic triterpenoid that potently activates the antioxidative transcription factor Nrf2 and inhibits the proinflammatory transcription factor NF-κB.

1474034-05-3
DC8224 Lifitegrast(SAR 1118) Featured

SAR 1118 is a potent tetrahydroisoquinoline (THIQ)-derived LFA-1/ICAM-1 antagonist for treating dry eye.

1025967-78-5
DC10925 SAR-100842 Featured

SAR-100842 (SAR100842) is a potent, selective, orally available antagonist of the Lysophosphatidic Acid 1 Receptor (LPA1 receptor) with IC50 of 31 nM in β-arrestin assays.

1195941-38-8
DC9600 Senicapoc Featured

Senicapoc(ICA17043) is a potent and selective Gardos channel blocker; blocked Ca(2+)-induced rubidium flux from human RBCs/ inhibited RBC dehydration with IC50s of 11 nM/30 nM, respectively. IC50 value: 11/30 nM [1] Target: Gardos channel in vitro: I

289656-45-7
DCAPI1485 Silodosin Featured

Silodosin(Rapaflo) is an α1-adrenoceptor antagonist with high uroselectivity. Silodosin causes practically no orthostatic hypotension (in contrast to other α1 blockers). Since Silodosin is a highly selective inhibitor of the α1A adrenergic receptor, it ca

160970-54-7
DC8592 Sivelestat (sodium salt hydrate) Featured

Sivelestat(ONO5046; LY544349; EI546) is a competitive inhibitor of human neutrophil elastase(IC50 = 44 nM; Ki=200 nM); also inhibited leukocyte elastase obtained from rabbit, rat, hamster and mouse.

201677-61-4
DC8500 SKQ1(Visomitin) Featured

SKQ1 prevents amyloid-beta-induced impairment of long-term potentiation in rat hippocampal slices.

934826-68-3
DC9732 Sufugolix(TAK-013) Featured

Sufugolix(TAK-013) is a non-peptide, orally-active, selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) (IC50 = 0.1 and 0.06 nM for affinity and in vitro inhibition, respectively).

308831-61-0
DC7306 TAK-438 Featured

TAK-438 is a novel P-CAB (potassium-competitive acid blocker) that reversibly inhibits H+/K+, ATPase with IC50 of 19 nM (pH 6.5), controls gastric acid secretion.

1260141-27-2
DC10390 TD139 Featured

TD139 is a novel high-affinity inhibitor of the galectin-3 carbohydrate binding domain with a Kd of 14 nM.

1450824-22-2
DC11026 Tecovirimat Featured

Tecovirimat (ST-246, Tpoxx) is a potent, orally bioavailable, first-in-class inhibitor of orthopoxvirus egress with EC50 of 0.01-0.6 uM against a panel of Orthopoxviruses; ST-246 is active against multiple orthopoxviruses, including vaccinia, monkeypox, c

869572-92-9
DC9148 Tolvaptan Featured

Tolvaptan is a selective, competitive arginine vasopressin receptor 2 antagonist with an IC50 of 1.28μM for the inhibition of AVP-induced platelet aggregation.

150683-30-0
DC11385 Trofinetide(NNZ2566) Featured

Trofinetide (NNZ-2566) is an analog of a molecule which is derived from IGF-1 and occurs naturally in the brain. IGF-1 is a growth factor stimulated by growth hormone.

853400-76-7
DC10737 Tropifexor (LJN452) Featured

Tropifexor (LJN452) is a highly potent non-bile Acid FXR Agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH).

1383816-29-2
DC10083 UK-371804 Featured

UK-371804 is a potent and selective uPA inhibitor with excellent enzyme potency (Ki 10 nM) and selectivity profile (4000-fold versus tPA and 2700-fold versus plasmin).

256477-09-5
DC10339 Vadadustat Featured

Vadadustat is a novel, titratable, oral hypoxia-inducible factor prolyl hydroxylase (HIF-PH) inhibitor in development for the treatment of anemia.

1000025-07-9
DC9816 Valbenazine(NBI-98854) Featured

Valbenazine(NBI-98854) is a potent and selective VMAT2 inhibitor..

1025504-45-3
DC1059 Lumacaftor(vx-809,vx809) Featured

VX-809 is a CFTR modulator with EC50 of 0.1 μM.

936727-05-8
DC9187 Mosapride Citrate

Mosapride citrate is a gastroprokinetic agent that acts as a selective 5HT4 agonist.

112885-42-4
DC9873 Selonsertib(GS-4997) Featured

Selonsertib(GS-4997)is an orally bioavailable inhibitor of apoptosis signal-regulating kinase 1 (ASK1), with potential anti-inflammatory, antineoplastic and anti-fibrotic activities.

1448428-04-3
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