| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11998 | IND-114338 | A novel antiprion compound with EC50 of 68 nM, significantly increases monoglycosylated/diglycosylated PrPSc.. |
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| DC11997 | IND125 | A novel brain penetrant antiprion compound with EC50 of 57 nM, prevents both PrP(Sc) accumulation and astrocytic gliosis in the cerebrum. |
|
| DC10168 | Anle138b Featured | Anle138b is a novel oligomer modulator. |
|
| DC73028 | ARN1468 | ARN1468 is an anti-prion, cellular active small molecule targeting SERPINA3 (ITC KD=26 uM), decreases prion accumulation and reduces PrPSc in the ScGT1 RML cell line with EC50 of 8.64 uM. |
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