Home > Inhibitors & Agonists > Ras-Raf-MAPK-ERK > Mixed Lineage Kinase (MLK)
Cat. No. Product name CAS No.
DC10503 GW806742X Featured

GW806742X is a novel VEGFR inhibitor.

DC9817 Necrosulfonamide (NSA) Featured

Necrosulfonamide (NSA) is a very specific and potent necrosis inhibitor with an IC50 less than 0.2 uM.

DC7889 URMC-099 Featured

URMC-099 is an orally bioavailable, brain penetrant mixed lineage kinase (MLK) inhibitor with IC50 of 19 nM, 42 nM, 14 nM, and 150 nM, for MLK1, MLK2, MLK3, and DLK, respectively, and also inhibits LRRK2 activity with IC50 of 11 nM.

DC43988 GW806742X hydrochloride

GW806742X hydrochloride, an ATP mimetic and a potent MLKL (Mixed Lineage Kinase Domain-Like protein) inhibitor, binds the MLKL pseudokinase domain with a Kd of 9.3 μM. GW806742X hydrochloride has activity against VEGFR2 (IC50=2 nM). GW806742X hydrochlorid

DC47569 MLKL-IN-1

MLKL-IN-1 is a covalent MLKL inhibitor with a KD of 50 μM.

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