Cat. No. | Product name | CAS No. |
DC11929 |
ME-344
A novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM. |
1374524-68-1 |
DC11866 |
AZD 3147
Featured
A potent, selective dual mTORC1 and mTORC2 inhibitor with enzyme IC50 of 1.5 nM. |
1101810-02-9 |
DC1001 |
FK-506 (Tacrolimus)
Featured
An immunosuppressive agent and macrolide antibiotic. |
104987-11-3 |
DC5084 |
AZD-8055
Featured
AZD-8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM. |
1009298-09-2 |
DC8377 |
CC-115
Featured
CC-115 is a dual inhibitor of DNA-dependent protein kinase (DNA-PK) and mammalian target of rapamycin (mTOR), with potential antineoplastic activity. |
1228013-15-7 |
DC8497 |
CC-223
Featured
CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity over the related lipid kinase PI3Kα (IC50=4 μM). |
1228013-30-6 |
DC10125 |
CZ415
Featured
CZ415 is a potent and highly selective mTOR inhibitor. |
1429639-50-8 |
DC1501 |
Everolimus
Featured
Everolimus (RAD001) is an mTOR inhibitor of FKBP12 with IC50 of 1.6-2.4 nM. |
159351-69-6 |
DC7014 |
GPI-1046
For the detailed information of GPI-1046, the solubility of GPI-1046 in water, the solubility of GPI-1046 in DMSO, the solubility of GPI-1046 in PBS buffer, the animal experiment (test) of GPI-1046, the cell expriment (test) of GPI-1046, the in vivo, in vitro and clinical trial test of GPI-1046, the EC50, IC50,and Affinity of GPI-1046, Please contact DC Chemicals.. |
186452-09-5 |
DC11151 |
ICSN3250 hydrochloride
ICSN3250 (ICSN-3250) hydrochloride is a halitulin-analogue that acts as a new-class, specific mTOR inhibitor through a mechanism distinct from previous mTOR inhibitors. |
1561902-79-1 |
DC11150 |
ICSN3250
ICSN3250 (ICSN-3250) is a halitulin-analogue that acts as a new-class, specific mTOR inhibitor through a mechanism distinct from previous mTOR inhibitors. |
1561902-73-5 |
DC7171 |
INK-128(Sapanisertib)
Featured
INK 128 is a potent and selective mTOR inhibitor with IC50 of 1 nM; >200-fold less potent to class I PI3K isoforms. |
1224844-38-5 |
DC3101 |
Ku-0063794
KU-0063794 is a potent and highly specific mTOR inhibitor for both mTORC1 and mTORC2 with IC50 ~10 nM. |
938440-64-3 |
DC7210 |
LY-303511(Nv-128)
Featured
LY303511, an inactive analogue of LY294002, is a mTOR inhibitor that did not inhibit PI3-K. |
154447-38-8 |
DC1006 |
OSI-027
Featured
OSI-027 is a selective and potent dual inhibitor of mTORC1 and mTORC2 with IC50 of 22 nM and 65 nM, respectively. |
936890-98-1 |
DC7482 |
Torkinib (PP242)
Featured
PP242 is a selective mTOR inhibitor with IC50 of 8 nM; targets both mTOR complexes with >10- and 100-fold selectivity for mTOR than PI3Kδ or PI3Kα/β/γ, respectively; also showed slightly weaker activity against BRD4 (Kd= 1.7 uM). |
1092351-67-1 |
DC11816 |
RapaLink-1
Featured
RapaLink-1 is a third-generation mTOR inhibitor that overcomes resistance to existing first- and second-generation inhibitors; blocks mTOR signaling of the F2108L mTOR and M2327I mTOR drug resistant mutants; RapaLink-1 is more potent mTOR inhibitor than rapamycin. |
1887095-82-0 |
DC1048 |
Rapamycin (Sirolimus)
Featured
Rapamycin (Sirolimus, AY-22989, WY-090217) is a specific mTOR inhibitor with IC50 of ~0.1 nM. - |
53123-88-9 |
DC11306 |
Secorapamycin A(Seco Rapamycin)
Featured
Seco-rapamycin(Secorapamycin A) is the first in vivo open-ring metabolite of rapamycin that does not affect mTOR.. |
147438-27-5 |
DCAPI1488 |
Temsirolimus
Featured
Temsirolimus is an inhibitor of ribosomal protein S6 phosphorylation and inhibits cell growth and clonogenic survival of cells in a concentration-dependent manner. |
162635-04-3 |
DC3117 |
Torin2
Featured
Torin 2 is a highly potent and selective mTOR inhibitor with IC50 of 0.25 nM, and also exhibits potent cellular activity against ATM/ATR/DNA-PK with EC50 of 28 nM, 35 nM and 118 nM, respectively. |
1223001-51-1 |
DC3118 |
Torin1
Featured
Torin1 is a potent inhibitor of mTOR with IC50 of 2-10 nM. |
1222998-36-8 |