DC12012 |
PD 404182
Featured
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PD 404182 is a high affinity inhibitor of KDO 8-P synthase (Ki = 26 nM). Also inhibits dimethylarginine dimethylaminohydrolase 1 (DDAH1). Exhibits antiangiogenic and antiviral activity in vitro. Putative antibiotic against gram-negative bacteria. |
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DC11892 |
Elsulfavirine
Featured
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A new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) for the treatment of HIV-1 infections, the prodrug of the active compound VM-1500A.. |
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DC11628 |
HIV-1 Integrase Inhibitor 1 |
A novel compound that disrupts the HIV-1 integrase LEDGF interaction. |
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DC11854 |
IDX899 |
A novel potent, selective HIV non-nucleoside reverse transcriptase inhibitor (NNRTI) with EC50 of 1, 1.3, 2.8 and 11 nM for WT, K103N, Y181C and K103N/Y181C, respectively. |
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DC11807 |
HIV InSTI-1 |
A potent HIV integrase strand transfer inhibitor (InSTIs) with IC50 of 8 nM in HIV replication assay. |
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DC11806 |
MK-0536 |
A potent HIV-1 integrase strand transfer inhibitor with IC50 of 33 nM, 9.5 nM, 40 nM, 20 nM and 237 nM for wt IN, IN Y143R, IN N155H, G118R and IN G140S-Q148H, respectively. |
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DC9029 |
Abacavir |
Abacavir is a powerful nucleoside analog reverse transcriptase inhibitor (NRTI) used to treat HIV and AIDS. |
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DC7058 |
Amprenavir
Featured
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Amprenavir (Agenerase) is a HIV protease inhibitor(Ki=0.6 nM) used to treat HIV infection. |
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DC3150 |
Atazanavir
Featured
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Atazanavir is a HIV protease inhibitor with Ki of 2.66 nM. |
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DC9480 |
Atazanavir (sulfate) |
Atazanavir sulfate is a sulfate salt form of atazanavir that is an highly potent HIV-1 protease inhibitor.
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DC10890 |
Bictegravir
Featured
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Bictegravir is a novel, potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM. |
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DC7007 |
BMS-538203 |
BMS-538203 is a highly efficient HIV integrase inhibitor and antiviral agent. |
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DC9700 |
BMS-707035
Featured
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BMS-707035 is a potent, specific, and reversible HIV-I integrase (IN) inhibitor that blocks HIV IN strand transfer activity. |
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DC8908 |
Darunavir ethanolate
Featured
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Darunavir ethanolate is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2). |
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DC11352 |
Delavirdine (mesylate) |
Delavirdine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) that selectively inhibits HIV-1 reverse transcriptase over DNA polymerase α and δ in vitro (IC50s = 0.26, 440, and >550 μM, respectively). |
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DC8897 |
Delavirdine |
Delavirdine(U 90152) is a potent non-nucleoside reverse transcriptase inhibitor (NNRTI). |
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DC7273 |
Dolutegravir
Featured
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Dolutegravir (DTG, GSK1349572) is an integrase inhibitor(IC50= 2.7 nM), modest activity against raltegravir-resistant signature mutants Y143R, Q148K, N155H, and G140S/Q148H. |
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DC10250 |
Dolutegravir Sodium
Featured
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Dolutegravir is a HIV integrase inhibitor with IC50 of 2.7 nM. |
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DC9308 |
Doravirine (MK-1439)
Featured
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Doravirine (MK-1439) is a non-nucleoside reverse transcriptase inhibitor. |
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DCAPI1479 |
Efavirenz |
Efavirenz is a nonnucleoside HIV-1 reverse transcriptase (RT) inhibitor which selectively inhibits the glucuronidation of 3'-Azido-3'-deoxythymidine β-D-glucuronide, Sodium Salt. Studies suggest that Efavirenz binds to a distinct site of reverse transcrip |
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DC5902 |
Emtricitabine
Featured
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Emtricitabine is a nucleoside analogue which inhibits the reverse nucleoside transcriptase enzyme. Structurally this antiviral agent is similar to Lamivudine. This agent is effective at targeting HIV and HBV viruses since these viruses replicate in a reve |
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DC4234 |
Etravirine |
Etravirine is a non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1). |
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DC11297 |
GS-9822 |
GS-9822 is a novel, potent NCINI with a higher barrier to resistance relative to early prototype NCINIs, including GS-9695. |
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DCAPI1505 |
Darunavir
Featured
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Darunavir(TMC114) is an HIV protease inhibitor,showed potent activity against COVID-19(SARS-COV-2) . |
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DC9473 |
HIV-1 integrase inhibitor |
HIV-1 integrase inhibitor ((Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid) is uesful for anti-HIV. |
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DC9472 |
HIV-1 integrase inhibitor 2 |
HIV-1 integrase inhibitor, in the treatment of human immunodeficiency virus (HIV) infection. |
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DC9476 |
NBD-556
Featured
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NBD-556 is small molecule mimetic of CD4, NBD-556 recognizes the HIV-1 envelope protein gp120 and induces restructuring of gp120 analogous to CD4 binding.
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DC9477 |
NBD-557 |
NBD-557 is a potentially HIV-1 inhibitor.
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DC10355 |
Nelfinavir
Featured
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Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
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DC9474 |
Nelfinavir (Mesylate) |
Nelfinavir(AG-1341) is a potent and orally bioavailable human immunodeficiency virus HIV-1 protease inhibitor (Ki=2 nM) and is widely prescribed in combination with HIV reverse transcriptase inhibitors for the treatment of HIV infection. |
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