| Cat. No. | Product Name | Field of Application | Chemical Structure |
|---|---|---|---|
| DC11826 | ASP-6537 | A novel potent, selective, reversible cyclooxygenase-1 (COX-1) inhibitor with IC50 of 4.9 nM. |
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| DC9900 | Acetaminophen Featured | Acetaminophen is a COX inhibitor for COX-1 and COX-2 with IC50 of 113.7 μM and 25.8 μM, respectively. |
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| DC9406 | Ampiroxicam | Ampiroxicam(CP65703) is a nonselective cyclooxygenase inhibitor uesd as anti-inflammatory drug. |
|
| DCAPI1491 | Celecoxib Featured | Celecoxib is a selective Cox-2 inhibitor (IC50 of 40 nM). Celecoxib shows low sensitivity against Cox-1 (IC50 of 15 μM). Celecoxib shows an anti-proliferative effect on nasopharyngeal carcinoma (NPC) cell lines including HNE1 (IC50of 32.86 μM) and CNE1-LM |
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| DC8911 | Deracoxib | Deracoxib, a selective cyclooxygenase-2 inhibitor, is a non-narcotic, non-steroidal anti-inflammatory drug (NSAID). |
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| DC9064 | Diclofenac sodium | Diclofenac Sodium is a non-selective COX inhibitor with IC50 of 60 and 220 nM for ovine COX-1 and -2, respectively. |
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| DCAPI1535 | Etodolac | Etodolac is a Cox-2 inhibitor with anti-inflammatory and analgesic activity. Etodolac is shown to inhibit growth and PCNA expression and induce cell cycle arrest in human hepatocellular carcinoma cell lines, in addition to suppressing the occurrence of ab |
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| DC10239 | Etoricoxib Featured | Etoricoxib is a new COX-2 selective inhibitor with anti-inflammatory, antipyretic, analgesic, and potential antineoplastic properties. |
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| DC8917 | Firocoxib | Firocoxib(ML 1785713) is a potent and selective cyclooxygenase (COX)-2 inhibitor with IC50 of 0.13 uM, 58 fold sensitivity for COX2 VSCOX1. |
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| DC7112 | FK 3311 Featured | FK 3311 is a selective inhibitor of COX-2; antiinflammatory agent. |
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| DCAPI1206 | Flurbiprofen (Ansaid) | Flurbiprofen (Ansaid) |
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| DC8965 | Ibuprofen | Ibuprofen (Motrin) is an anti-inflammatory inhibitor targeting COX-1 and COX-2, of which is used for pain relief, fever reduction and for reducing swelling. |
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| DC9100 | Ketorolac Tromethamine | Ketorolac (Ketorolac tromethamine, Toradol) is a non-selective COX inhibitor with strong analgesic activity. |
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| DC8751 | Licofelone | Licofelone is a dual COX/LOX inhibitor being considered as a treatment for osteoarthritis. |
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| DCAPI1565 | Loxoprofen Sodium | Loxoprofen is a non-steroidal anti-inflammatory drug that is quickly converted to the trans-alcohol metabolite. It is similar to ibuprofen and naproxen, while also being a Cycloxygenase (COX) inhibitor. |
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| DC9000 | Naproxen sodium | Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively. |
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| DC8982 | Naproxen | Naproxen is a COX inhibitor for COX-1 and COX-2 with IC50 of 8.7 μM and 5.2 μM, respectively. |
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| DCAPI1342 | Nepafenac | Nepafenac |
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| DC8806 | NS-398 Featured | NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). |
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| DC10255 | Parecoxib | Parecoxib is a selective COX2 inhibitor. |
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| DCAPI1503 | PARECOXIB SODIUM | PARECOXIB SODIUM |
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| DC9071 | Piroxicam | Piroxicam (Feldene) is a non-selective COX inhibitor with an IC50 of 6 mM. |
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| DC11373 | Polmacoxib | Polmacoxib is an inhibitor of cyclooxygenase 2 (COX-2) and the carbonic anhydrase subtypes I (CAI) and CAII. |
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| DC7030 | SC-560 Featured | SC-560 is a member of the diaryl heterocycle class of cyclooxygenase (COX) inhibitors which includes celecoxib (Celebrex™) and rofecoxib (Vioxx™). |
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| DC10268 | (+/-)-Sulfinpyrazone | Sulfinpyrazone is one of the most studied platelet COX inhibitors, also a uricosuric agent that competitively inhibits uric acid reabsorption in kidney proximal tubules. |
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| DC11263 | COX-1 Inhibitor IV（TFAP） Featured | The COX-1 Inhibitor IV, TFAP controls the biological activity of COX-1. |
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| DC9405 | Valdecoxib | Valdecoxib (SC 65872) is a COX-2 selective inhibitor with an IC50 value of 5 nM. |
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| DC9408 | Zaltoprofen | Zaltoprofen(CN100) is an inhibitor of COX for treatment of arthritis. |
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| DC28159 | DuP-697 | DuP-697 is a member of the vicinal diaryl heterocycles and a potent, irreversible, selective and orally active COX-2 inhibitor (IC50 of 10 nM and 800 nM for human COX-2 and COX-1, respectively). DuP-697 exerts antiproliferative (IC50 of 42.8 nM), antiangiogenic and apoptotic effects on HT29 colorectal cancer cells. DuP-697 inhibits prostaglandin synthesis and has anti-inflammatory, anticancer and antipyretic effects. |
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| DC28383 | Desmethyl Celecoxib Featured | Desmethyl Celecoxib (compound 3b) is a selective cyclooxygenase-2 (COX-2) inhibitor (IC50=32 nM) with anti-inflammatory activities. Desmethyl Celecoxib is an analog of Celecoxib and with the optimal yield of 75%. |
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