| DC22584 |
Mavorixafor(AMD-070)
Featured
|
A potent and selective antagonist of CXCR4 with IC50 of 13 nM in a CXCR4 125I-SDF inhibition binding assay. |
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| DC11667 |
PF-592379 |
A potent, selective, orally active agonist of dopamine D3 receptor with EC50 of 21 nM. |
|
| DC5083 |
Cinacalcet (AMG-073) HCl
Featured
|
AMG-073 HCl (Cinacalcet HCl) represents a new class of compounds for the treatment of hyperparathyroidism. |
|
| DC7357 |
Anamorelin
Featured
|
Anamorelin(RC1291; ONO-7643) is a synthetic orally active ghrelin receptor agonist which is under development for the management of non-small lung cancer associated cachexia/anorexia. |
|
| DC11095 |
ATR-101 free base |
ATR-101 (PD-132301, Nevanimibe) is a selective and potent inhibitor of ACAT1 with IC50 of 52 nM. |
|
| DC8799 |
Avanafil(TA-1790)
Featured
|
Avanafil(TA-1790) is a potent and highly selective phosphodiesterase-5(PDE-5) inhibitor(IC50=5.2 nM) for erectile dysfunction; lower selectivity against PDE1, PDE6, and PDE11. |
|
| DC8801 |
Cinacalcet (AMG-073)
Featured
|
Cinacalcet(AMG-073) is an orally active, second-generation calcimimetic compound; AMG 073 represents a new class of compounds for the treatment of hyperparathyroidism. |
|
| DCAPI1241 |
Doxercalciferol (Hectorol)
Featured
|
Doxercalciferol is a synthetic vitamin D2 analog, suppressing parathyroid synthesis and secretion, used to treat secondary hyperparathyroidism and metabolic bone disease. |
|
| DC8177 |
Enclomiphene citrate
Featured
|
Enclomiphene is a non-steroidal estrogen receptor antagonist that promotes gonadotropin-dependent testosterone secretion by the testes. |
|
| DC7020 |
Ibutamoren mesylate
Featured
|
Ibutamoren mesylate (MK-0677) is an orally active nonpeptide growth hormone (GH) secretagogue. |
|
| DC6577 |
Paricalcitol |
Paricalcitol |
|
| DC10531 |
PCO371
Featured
|
PCO371 is a novel, orally active small molecule that acts as a full agonist of PTHR1. |
|
| DC11664 |
PF-00446687 hydrochloride |
PF-00446687 hydrochloride (PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
|
| DC11665 |
PF-00446687 |
PF-00446687(PF-446687) is a potent, selective melanocortin-4 receptor (MC4R) agonist with EC50 of 12 nM. |
|
| DC7480 |
PF-3274167（cligosiban）
Featured
|
PF-3274167 is a high-affinity nonpeptide oxytocin receptor (OTR) antagonist, with Ki of 9.5 nM. |
|
| DC5901 |
Tadalafil
Featured
|
Tadalafil is a potent and selective inhibitor of Phosphodiesterase-5 (PDE5) This compound prevents the breakdown of phosphodiesterases, many of which are used as secondary messengers. By preventing the breakdown of these messenger molecules, tadalafil can |
|
| DC4133 |
Udenafil |
Udenafil is a new phosphodiesterase type 5 (PDE5) inhibitor used to treat erectile dysfunction (ED) |
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