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| Cat. No. | Product Name | Field of Application | Chemical Structure |
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| DC7961 | (-)MK-801 maleate Featured | (-)-MK 801 Maleate is the enantiomer of (+)-MK-801; (+)-MK-801 is a highly potent and selective non-competitive NMDA glutamate receptor antagonist . |
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| DC9624 | Sparteine sulfate pentahydrate Featured | (-)-Sparteine sulfate pentahydrate is a class 1a antiarrhythmic agent and a sodium channel blocker. |
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| DC10625 | (+)-Bicuculline Featured | (+)-Bicuculline is a competitive antagonist of GABAA receptors with IC50 of 2 μM, also blocks Ca(2+)-activated potassium channels. |
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| DC9450 | (R)-Baclofen | (R)-Baclofen(STX209) is a selective GABAB receptor agonist. |
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| DC10388 | (R)-BPO-27 | (R)-BPO-27 is a potent CFTR inhibitor with an IC50 of 4 nM |
-BPO-27.gif)
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| DCF-001 | Tetrandrine | >98%,Standard References |
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| DCJ-030 | Galanthamine | >98%,Standard References |
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| DCL-011 | Capsaicin | >98%,Standard References |
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| DC7876 | 7ACC2 Featured | 7ACC2 is a new potent MCT inhibitor with IC50 of 11 nM for inhibition of [14C]-lactate influx; new antitumor treatment targeting lactate transport in cancer cells. |
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| DC11933 | RX 871024 | A imidazoline compound that stimulate insulin release by inhibition of ATP-dependent K+ channels and inducing of Ca2+ mobilization in mouse pancreatic beta-cells. |
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| DC11646 | ML67-33 Featured | A low micromolar (EC50=9.7 uM, K2P2.1), selective activator of temperature- and mechano-sensitive K2P potassium channels. |
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| DC11502 | 2-APB | A membrane permeable IP3 receptor antagonist and broad TRP channels (TRPC5, TRPM2) blcoker. |
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| DC10801 | AMPA/kainate antagonist-1 Featured | A novel Non-competitive AMPA/kainate antagonist. |
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| DC10808 | AMPA/kainate antagonist-3 Featured | A novel Non-competitive AMPA/kainate antagonist. |
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| DC10802 | AMPA/kainate antagonist-2 | A novel Non-competitive AMPA/kainate antagonist. |
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| DC11515 | Azeloprazole | A novel potent proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
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| DC11546 | Azeloprazole sodium | A novel potent, orally active proton pump inhibitor that irreversibly inhibits H+,K+-ATPase activity with IC50 of 0.28 uM. |
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| DC12019 | RY796 | A novel potent, selective Kv2 channel inhibitor that potently inhibits Kv2.1 and Kv2.2 with IC50 of 0.14 and 0.09 uM, respectively. |
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| DC12004 | NS19504 | A novel selective, small molecule large-conductance Ca(2+)-activated K(+) channel (BKCa, KCa1.1, MaxiK) positive modulator with EC50 of 11 uM. |
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| DC12000 | AUT2 | A novel specific, cell permeant modulator of Kv3 channels with EC50 of 0.9 and 1.9 uM for Kv3.1b and Kv3.2a, respectively. |
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| DC11676 | NS15370 | A novel, highly potent positive modulator of Kv7 channels with EC50 of 100 nM (Kv7.2-Kv7.5). |
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| DC11984 | AMG 8379 | A potent and selective voltage-gated sodium channel Nav1.7 antaognist with IC50 of 8.5 nM. |
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| DC11944 | VU714 | A potent inwardly rectifying K+ channel Kir7.1 inhibitor with IC50 of 5.6 uM in T1+ flux assays. |
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| DC11753 | BL-1249 Featured | BL-1249 is a nonsteroidal anti-inflammatory drug (NSAID) and a potassium channel activator. BL-1249 exhibits more selective for the bladder (EC50 of 1.26 μM) than vascular tissue (EC50 of 21.0 μM). BL-1249 extracellular application activates all TREK subfamily members but has no effect on other K2P subfamilies. BL-1249 potently activates K2P2.1 (TREK-1) and K2P10.1 (TREK-2) with EC50 values of 5.5 μM and 8.0 μM, respectively |
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| DC11943 | MRT2000769 | A potent Kir7.1 inhibitor with IC50 of 2.0 uM, induces long-lasting uterine contractility similar to those observed with VU590.. |
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| DC11839 | Org 25543 | A potent, highly selective glycine transporter 1 (GlyT2) inhibitor with IC50 of 16 nM with negligible affinity for GlyT1.. |
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| DC11675 | Synta-66 | A potent, selective CRAC channel Orai1 blocker with IC50 of 3 uM. |
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| DC11838 | Org 25935 | A potent, selective glycine transporter 1 (GlyT1) inhibitor with IC50 of 100 nM. |
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| DC11967 | PF-06649298 | A potent, selective inhibitor of the Na+/citrate transporter NaCT (SLC13A5) that shows inhibition of citrate uptake in the HEKNaCT cells with IC50 of 0.41 uM. |
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| DC11507 | CLP257 Featured | CLP257 (CLP-257) is a potent, selective K+-Cl- cotransporter KCC2 activator with EC50 of 616 nM; displays selectivity for KCC2 over other KCC family members, NKCC1 and GABAA receptors, and a panel of 55 other receptors; restores impaired Cl(-) transport i |
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